Obesity and diabetes are strongly associated with metabolic and cardiovascular disorders
including dyslipidemia, coronary artery disease, hypertension, and heart failure. Adipose …

Background Branched chain amino acids (BCAA) can impair insulin signaling, and cardiac
insulin resistance can occur in the failing heart. We, therefore, determined if cardiac BCAA …

Joint injury and osteoarthritis affect millions of people worldwide, but attempts to generate
articular cartilage using adult stem/progenitor cells have been unsuccessful. We hypothesized …

The prognosis and treatment outcomes of heart failure (HF) patients rely heavily on disease
etiology, yet the majority of underlying signaling mechanisms are complex and not fully …

Ocimum tenuiflorum is a widely used medicinal plant since ancient times and still continues
to be irreplaceable due to its properties. The plant has been explored chemically and …

Background The mycobiome is the fungal component of the gut microbiome and is implicated
in several autoimmune diseases. However, its role in MS has not been studied. Methods In …

Biomechanical stress and cytoskeletal remodeling are key determinants of cellular homeostasis
and tissue responses to mechanical stimuli and injury. Here we document the increased …

Importance Current studies assessing the risk of stroke, myocardial infarction (MI), and death
in patients undergoing intravitreal anti–vascular endothelial growth factor (VEGF) therapy …

Ocimum is one of the most revered medicinally useful plants which have various species.
Each of the species is distinct in terms of metabolite composition as well as the medicinal …

Introduction This manuscript describes data from an original study, simulating a tele-glaucoma
programme in an established clinic practice with an interdisciplinary team. This is a ‘real …