Cervical spine alignment, sagittal deformity, and clinical implications: a review

…, JA Tang, JS Smith, FL Acosta, TS Protopsaltis… - … of Neurosurgery: Spine, 2013 - thejns.org
This paper is a narrative review of normal cervical alignment, methods for quantifying
alignment, and how alignment is associated with cervical deformity, myelopathy, and adjacent-…

The T1 pelvic angle, a novel radiographic measure of global sagittal deformity, accounts for both spinal inclination and pelvic tilt and correlates with health-related …

T Protopsaltis, F Schwab, N Bronsard, JS Smith… - JBJS, 2014 - journals.lww.com
Background: Adult spinal deformity is a prevalent cause of pain and disability. Established
measures of sagittal spinopelvic alignment such as sagittal vertical axis and pelvic tilt can be …

Prospective multicenter assessment of perioperative and minimum 2-year postoperative complication rates associated with adult spinal deformity surgery

…, GM Mundis, TJ Errico, HJ Kim, TS Protopsaltis… - … of Neurosurgery: Spine, 2016 - thejns.org
OBJECTIVE Although multiple reports have documented significant benefit from surgical
treatment of adult spinal deformity (ASD), these procedures can have high complication rates. …

Reliability assessment of a novel cervical spine deformity classification system

…, R Hostin, JK Scheer, TS Protopsaltis… - … of Neurosurgery: Spine, 2015 - thejns.org
OBJECT Despite the complexity of cervical spine deformity (CSD) and its significant impact
on patient quality of life, there exists no comprehensive classification system. The objective of …

Prospective multicenter assessment of risk factors for rod fracture following surgery for adult spinal deformity

…, V Lafage, FJ Schwab, T Protopsaltis… - … of Neurosurgery: Spine, 2014 - thejns.org
Object Improved understanding of rod fracture (RF) following adult spinal deformity (ASD)
surgery could prove valuable for surgical planning, patient counseling, and implant design. …

Outcomes of operative and nonoperative treatment for adult spinal deformity: a prospective, multicenter, propensity-matched cohort assessment with minimum 2-year …

…, GM Mundis, T Errico, HJ Kim, TS Protopsaltis… - …, 2016 - journals.lww.com
BACKGROUND: High-quality studies that compare operative and nonoperative treatment for
adult spinal deformity (ASD) are needed. OBJECTIVE: To compare outcomes of operative …

Postischemic cerebrovascular E-selectin expression mediates tissue injury in murine stroke

…, S Kiss, J Mocco, LJ Kim, TS Protopsaltis… - Stroke, 2000 - Am Heart Assoc
Background and Purpose—Although the deleterious role of several proinflammatory mediators,
including P-selectin, in reperfused stroke is well established, the role of E-selectin has …

Role of pelvic translation and lower-extremity compensation to maintain gravity line position in spinal deformity

…, S Liu, JM Vital, B Ilharreborde, TS Protopsaltis… - … of Neurosurgery: Spine, 2016 - thejns.org
OBJECT Previous forceplate studies analyzing the impact of sagittal-plane spinal deformity
on pelvic parameters have demonstrated the compensatory mechanisms of pelvis translation …

How the neck affects the back: changes in regional cervical sagittal alignment correlate to HRQOL improvement in adult thoracolumbar deformity patients at 2-year …

TS Protopsaltis, JK Scheer, JS Terran, JS Smith… - … of Neurosurgery: Spine, 2015 - thejns.org
OBJECT Regional cervical sagittal alignment (C2–7 sagittal vertical axis [SVA]) has been
shown to correlate with health-related quality of life (HRQOL). The study objective was to …

T1 pelvic angle (TPA) effectively evaluates sagittal deformity and assesses radiographical surgical outcomes longitudinally

DJ Ryan, TS Protopsaltis, CP Ames, R Hostin… - Spine, 2014 - journals.lww.com
Study Design. Retrospective review of a multicenter database of consecutive patients
undergoing 3-column osteotomy for treatment of adult spinal deformity (ASD). Objective. To …