β-Coronaviruses are a family of positive-strand enveloped RNA viruses that includes the
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Much is known regarding …

Here we present version 2.0 of HADDOCK, which incorporates considerable improvements
and new features. HADDOCK is now able to model not only protein–protein complexes but …

Endocytic recycling returns proteins to the plasma membrane in many physiological contexts.
Studies of these events have helped to elucidate fundamental mechanisms that underlie …

In comparison to the internalization pathways of endocytosis, the recycling pathways are less
understood. Even less defined is the process of regulated recycling, as few examples exist …

The ARF GTP binding proteins are believed to function as regulators of membrane traffic in
the secretory pathway. While the ARF1 protein has been shown in vitro to mediate the …

Five flavonoids were isolated from the resin part of the female inflorescences of Humulus
lupulus, together with four known hop flavonoids, ie xanthohumol, 2′,4′,6′,4-tetrahydroxy-3…

During cell migration, integrins are redistributed from focal adhesions undergoing disassembly
at the cell’s trailing edges to new focal adhesions assembling at leading edges. The …

We have shown previously that the ADP- ribosylation factor (ARF)-6 GTPase localizes to the
plasma membrane and intracellular endosomal compartments. Expression of ARF6 mutants …

As with other complex cellular functions, intracellular membrane transport involves the
coordinated engagement of a series of organelles and machineries; however, the molecular basis …

Signaling through the Ror2 receptor tyrosine kinase promotes invadopodia formation for
tumor invasion. Here, we identify intraflagellar transport 20 (IFT20) as a new target of this …