ContextLumbar diskectomy is the most common surgical procedure performed for back and
leg symptoms in US patients, but the efficacy of the procedure relative to nonoperative care …

Background Management of degenerative spondylolisthesis with spinal stenosis is
controversial. Surgery is widely used, but its effectiveness in comparison with that of nonsurgical …

… Site Enrollers (In order by randomized enrollment): William Abdu (Dartmouth-Hitchcock
Medical Center); David Montgomery, Harry Herkowitz (William Beaumont Hospital); Ted Conliffe, …

Background Ketamine is an N-methyl-d-aspartate receptor antagonist that has been shown
to be useful in the reduction of acute postoperative pain and analgesic consumption in a …

Study Design. Concurrent prospective randomized and observational cohort studies.
Objective. To assess the 8-year outcomes of surgery versus nonoperative care. Summary of …

Study Design. A prospective study of 17,774 patients who consulted spine centers in which
the impact of spinal disorders and comorbidities on physical functional status were evaluated…

Study Design. Randomized trial with a concurrent observational cohort study. Objective. To
compare 8-year outcomes of surgery with nonoperative care for symptomatic lumbar spinal …

Study Design. Clinical trial subgroup analysis. Objective. To compare outcomes of different
fusion techniques treating degenerative spondylolisthesis (DS). Summary of Background …

Study Design. Prospective observational cohorts. Objective. To describe sociodemographic
and clinical features, and nonoperative (medical) resource utilization before enrollment, in …

Study Design. A cross-sectional study of 15,974 patients with spine disease from 26 members
of the National Spine Network. Objectives. To use functional status measures and clinical …