Purpose Safety concerns regarding the application of bone morphogenetic proteins (BMPs)
have been highlighted in recent years. It is noted that both BMP and their receptors being …

A metaphyseal bone defect due to infection, tumor or fracture leads to loss of cancellous and
cortical bone. An animal model separating the cancellous and cortical healing was used …

OBJECTIVE Bone morphogenetic protein (BMP) has been increasingly used in spinal
surgery to promote arthrodesis. Because BMP stimulates cellular proliferation, its …

The management of critical-sized bone defects caused by nonunion, trauma, infection,
malignancy, pseudoarthrosis, and osteolysis poses complex reconstruction challenges for …

Once thought to have revolutionized therapeutic intervention in surgery, Recombinant
Human Bone Morphogenic Protein 2 (rhBMP2) is now in its second decade of sustained …

BACKGROUND CONTEXT Large observational studies on potential oncogenic effects of
recombinant human bone morphogenetic protein (rhBMP) in spine fusion surgery are limited …

Frakturen und Osteotomien führen zu einer knöchernen Diskontinuität mit Spaltbildung. Ist
die Knochenheilung über einen Zeitraum von 6 Monaten gestört und hat nicht zu einer …

Use of Bone Morphogenetic Protein in Pediatric Cranioplasty... : Journal of Craniofacial Surgery
Use of Bone Morphogenetic Protein in Pediatric Cranioplasty With Pre- and Postoperative …

Bone grafts or substitutes are used in spinal surgery to fill defects, to bridge defects or to
promote spondylodesis. The physiological process is similar to that of fracture healing and …

Bone tissue is commonly transplanted during orthopedic surgeries, primarily for the
management of bone defects caused by trauma or various orthopedic conditions including …