Background In determining the etiology of pain of discogenic origin, attention is paid to the
role of neurotrophic factors, such as brain-derived neurotrophic factor (BDNF). Considering …

OBJECTIVE Long-term outcomes of single-level lumbar arthroplasty are understood to be
very good, with the most recent Investigational Device Exemption (IDE) trial showing a< 5 …

Purpose Microdiscectomy is the current gold standard surgical treatment for primary lumbar
disc herniations that fail non-surgical measures. Herniated nucleus pulposus is the …

Background The motion preserving benefits of lumbar total disc replacement (LTDR) are
well established. There is a paucity of long-term follow-up data on the M6-L prosthesis. The …

Study Design Systematic Review. Objectives To systematically review the clinical outcomes,
re-operation, and complication rates of lumbar TDR devices at mid-to long-term follow-up …

The number of spinal procedures and spinal fusions continues to grow. Although fusion
procedures have a high success rate, they have inherent risks such as pseudarthrosis and …

Objective: To perform a retrospective analysis of patients with degenerative disc disease of
the lumbar spine undergoing arthrodesis or lumbar arthroplasty in terms of functional …

Objective The purpose of this study was to assess the impact of facet tropism on the facet
contact force and facet capsule strain after artificial cervical disc replacement (ACDR) …

We read with great interest the manuscript entitled,“Long-term results of the NECK trial—
implanting a disc prosthesis after cervical anterior discectomy cannot prevent adjacent …

Total disc replacement, using an artificial intervertebral disc designed for the lumbar spine,
is proposed as an alternative to spinal fusion in patients with degenerative disc disease …