Intervertebral disc degeneration and osteoarthritis: a common molecular disease spectrum
Intervertebral disc degeneration (IDD) and osteoarthritis (OA) affecting the facet joint of the
spine are biomechanically interdependent, typically occur in tandem, and have considerable …
spine are biomechanically interdependent, typically occur in tandem, and have considerable …
The role of nerve fibers and their neurotransmitters in regulating intervertebral disc degeneration
K Sun, J Jiang, Y Wang, X Sun, J Zhu, X Xu… - Ageing Research …, 2022 - Elsevier
Intervertebral disc degeneration (IVDD) has been the major contributor to chronic lower back
pain (LBP). Abnormal apoptosis, senescence, and pyroptosis of IVD cells, extracellular …
pain (LBP). Abnormal apoptosis, senescence, and pyroptosis of IVD cells, extracellular …
Tension-activated nanofiber patches delivering an anti-inflammatory drug improve repair in a goat intervertebral disc herniation model
AP Peredo, SE Gullbrand, CS Friday… - Science Translational …, 2023 - science.org
Conventional microdiscectomy treatment for intervertebral disc herniation alleviates pain but
does not repair the annulus fibrosus, resulting in a high incidence of recurrent herniation …
does not repair the annulus fibrosus, resulting in a high incidence of recurrent herniation …
[HTML][HTML] Degenerative disc disease of the spine: from anatomy to pathophysiology and radiological appearance, with morphological and functional considerations
L Scarcia, M Pileggi, A Camilli, A Romi… - Journal of Personalized …, 2022 - mdpi.com
Degenerative disc disease is a common manifestation in routine imaging of the spine; this
finding is partly attributable to physiological aging and partly to a pathological condition, and …
finding is partly attributable to physiological aging and partly to a pathological condition, and …
Epidemiology of work-related musculoskeletal disorders
R Bonfiglioli, Y Caraballo-Arias… - Current Opinion in …, 2022 - journals.lww.com
After decades of research, we still find gaps in the literature on WRMSDs, especially
concerning diagnostic criteria, workplace exposure assessment, and compensation. The …
concerning diagnostic criteria, workplace exposure assessment, and compensation. The …
[HTML][HTML] The role of oxidative stress in intervertebral disc cellular senescence
F Cheng, H Yang, Y Cheng, Y Liu, Y Hai… - Frontiers in …, 2022 - frontiersin.org
With the aggravation of social aging and the increase in work intensity, the prevalence of
spinal degenerative diseases caused by intervertebral disc degeneration (IDD) has …
spinal degenerative diseases caused by intervertebral disc degeneration (IDD) has …
Bioinspired Construction of Annulus Fibrosus Implants with a Negative Poisson's Ratio for Intervertebral Disc Repair and Restraining Disc Herniation
Y Jiang, J Wang, R Wu, L Qi, L Huang… - Bioconjugate …, 2023 - ACS Publications
Inspired by the negative Poisson's ratio (NPR) effects of the annulus fibrosus (AF) in
intervertebral discs (IVDs), we designed a re-entrant honeycomb model and then 3D printed …
intervertebral discs (IVDs), we designed a re-entrant honeycomb model and then 3D printed …
[HTML][HTML] Strontium Ranelate Ameliorates Intervertebral Disc Degeneration via Regulating TGF-β1/NF-κB Axis
R Sun, J Zhu, K Sun, L Gao, B Zheng… - International Journal of …, 2023 - ncbi.nlm.nih.gov
Intervertebral disc degeneration (IVDD) is a prevalent and debilitating condition
characterized by chronic back pain and reduced quality of life. Strontium ranelate (SRR) is a …
characterized by chronic back pain and reduced quality of life. Strontium ranelate (SRR) is a …
Ex vivo intervertebral disc cultures: degeneration-induction methods and their implications for clinical translation
E Salzer, TC Schmitz, VHM Mouser… - European Cells and …, 2023 - eprints.whiterose.ac.uk
Because low back pain is frequently a result of intervertebral disc degeneration (IVDD),
strategies to regenerate or repair the IVD are currently being investigated. Often, ex vivo disc …
strategies to regenerate or repair the IVD are currently being investigated. Often, ex vivo disc …
[HTML][HTML] Comparative study of outcomes between allograft intervertebral disc transplantation and anterior cervical discectomy and fusion: a retrospective cohort study …
J Zhang, D Ruan, A Xuan, Q He, C Zhang, C Xu… - European Spine …, 2023 - Springer
Abstract Purpose Adjacent segment degeneration (ASDeg) after anterior cervical
discectomy and fusion (ACDF) seriously affects the long-term efficacy of the operation …
discectomy and fusion (ACDF) seriously affects the long-term efficacy of the operation …