A review of the biologic effects of spine implant debris: Fact from fiction

NJ Hallab - SAS journal, 2009 - Elsevier
BACKGROUND: Biologic-reactivity to implant-debris is the primary determinant of long-term
clinical performance. The following reviews: 1) the physical aspects of spinal-implant debris …

Orthopedic implant cobalt‐alloy particles produce greater toxicity and inflammatory cytokines than titanium alloy and zirconium alloy‐based particles in vitro, in …

A Dalal, V Pawar, K McAllister… - Journal of Biomedical …, 2012 - Wiley Online Library
The performance of total joint arthroplasty (TJA) depends on the size/shape, material, and
amounts of implant debris. Much remains unknown in terms of which types of debris are …

Macrophage reactivity to different polymers demonstrates particle size‐ and material‐specific reactivity: PEEK‐OPTIMA® particles versus UHMWPE particles in the …

NJ Hallab, K McAllister, M Brady… - Journal of Biomedical …, 2012 - Wiley Online Library
Biologic reactivity to orthopedic implant debris is generally the main determinant of long‐
term clinical performance where released polymeric particles of Ultra‐high molecular weight …

Quantifying subtle but persistent peri-spine inflammation in vivo to submicron cobalt–chromium alloy particles

NJ Hallab, FW Chan, ML Harper - European Spine Journal, 2012 - Springer
Purpose We evaluated the consequences of cobalt–chromium alloy (CoCr) wear debris
challenge in the peri-spine region to determine the inflammation and toxicity associated with …

Characterizing fretting damage in different test media for cardiovascular device durability testing

JD Weaver, L Ramirez, S Sivan, M Di Prima - Journal of the mechanical …, 2018 - Elsevier
In vitro durability tests of cardiovascular devices are often used to evaluate the potential for
fretting damage during clinical use. Evaluation of fretting damage is important because …

Metal Ion Sensitivity

WM Mihalko, CR Olinger - Handbook of Spine Technology, 2021 - Springer
Metal hypersensitivity to biomaterial alloys have been reported since the 1970s. While most
reports have been in the total joint literature, in the last 10 years isolated spinal implant …

[CITATION][C] Zkoušení a hodnocení korozní odolnost vybraných kovových biomateriálů

J Hlinka - 2013 - dspace.vsb.cz
Tato diplomová práce si klade za cíl představit základní skupiny biomateriálů, jejich primární
použití a poukázat jak na jejich výhody, tak jejich nevýhody. Jsou zde také diskutovány …