Canine models of spine disorders

NN Lee, JS Kramer, AM Stoker, CC Bozynski… - JOR …, 2020 - Wiley Online Library
Neck and low back pain are common among the adult human population and impose large
social and economic burdens on health care and quality of life. Spine‐related disorders are …

Injectable cellulose-based hydrogels as nucleus pulposus replacements: Assessment of in vitro structural stability, ex vivo herniation risk, and in vivo biocompatibility

HA Lin, DM Varma, WW Hom, MA Cruz… - Journal of the …, 2019 - Elsevier
Current treatments for intervertebral disc degeneration and herniation are palliative only and
cannot restore disc structure and function. Nucleus pulposus (NP) replacements are a …

Does pedicle screw fixation of the subaxial cervical spine provide adequate stabilization in a multilevel vertebral body fracture model? An in vitro biomechanical study

J Duff, MM Hussain, N Klocke, JA Harris… - Clinical …, 2018 - Elsevier
Background Cervical vertebral body fractures generally are treated through an anterior-
posterior approach. Cervical pedicle screws offer an alternative to circumferential fixation …

Comparison of four in vitro test methods to assess nucleus pulposus replacement device expulsion risk

T Rahman, MJ Kibble, G Harbert, N Smith… - JOR …, 2024 - Wiley Online Library
Abstract Background Nucleus replacement devices (NRDs) are not routinely used in clinic,
predominantly due to the risk of device expulsion. Rigorous in vitro testing may enable …

[HTML][HTML] Nucleus Disc Replacement: Design and Material Selection FEA Analysis

A Vanaclocha, V Vanaclocha, CM Atienza… - Advances in Materials …, 2022 - hindawi.com
Study Design. We selected the materials and implant design and performed Finite Element
Analysis (FEA) studies. Background. Nucleus disc replacements, implanted since 1960 …

Stabilizing effect of the rib cage on adjacent segment motion following thoracolumbar posterior fixation of the human thoracic cadaveric spine: A biomechanical study

MD Rahm, DM Brooks, JA Harris, RA Hart… - Clinical …, 2019 - Elsevier
Background Although the rib cage provides substantial stability to the thoracic spine, few
biomechanical studies have incorporated it into their testing model, and no studies have …

Replacing the nucleus pulposus for degenerative disc disease and disc herniation: disc preservation following discectomy

U Chamoli, M Lam, AD Diwan - Handbook of Spine Technology, 2021 - Springer
Low back pain is the leading cause of years lived with disability worldwide and thus a
significant burden on the economy and healthcare systems. Degenerative changes and/or …

[PDF][PDF] Research Article Nucleus Disc Replacement: Design and Material Selection FEA Analysis

A Vanaclocha, V Vanaclocha, CM Atienza, P Clavel… - 2022 - academia.edu
Study Design. We selected the materials and implant design and performed Finite Element
Analysis (FEA) studies. Background. Nucleus disc replacements, implanted since 1960 …

Development and Functional Evaluation of Injectable Cellulose-based Hydrogels as Nucleus Pulposus Replacements for Intervertebral Disc Repair

HA Lin - 2018 - search.proquest.com
The intervertebral disc (IVD) is a complex, fibrocartilaginous tissue interposed between the
vertebral bodies of the spine. It plays important roles such as facilitating both flexibility and …

Development of Translational Models for Intervertebral Disc Degeneration Using a Comparative Approach for Canine and Human Patients

NN Lee - 2020 - search.proquest.com
Intervertebral discs (IVDs) are unique musculoskeletal tissues within functional spinal unit
organs comprising the spinal column that distribute loads and allow complex movements for …