[HTML][HTML] Comprehensive narrative review on the analysis of outcomes from cell transplantation clinical trials for discogenic low back pain

J Schol, D Sakai - North American Spine Society Journal (NASSJ), 2023 - Elsevier
Background Intervertebral disc (IVD) degeneration is one of the primary causes of low back
pain (LBP) and despite a prominent prevalence, present treatment options remain …

Protocols and techniques for orthobiologic procedures

M Khadavi, A Pourcho, L Podesta - Physical Medicine and …, 2023 - pmr.theclinics.com
Although the basic science and clinical research for orthobiologic therapies grows
exponentially, outcome data comparing the variety of techniques remain relatively …

The Analgesic Efficacy of Intradiscal Injection of Bone Marrow Aspirate Concentrate and Culture-Expanded Bone Marrow Mesenchymal Stromal Cells in Discogenic …

YF Her, E Kubrova, GA Martinez Alvarez… - Journal of Pain …, 2022 - Taylor & Francis
Pain originating from the intervertebral disc (discogenic pain) is a prevalent manifestation of
low back pain and is often challenging to treat. Of recent interest, regenerative medicine …

[HTML][HTML] FactFinders for patient safety: Understanding potential procedure-related complications: RFN/multifidus atrophy, intradiscal biologics, and facet cyst rupture

M Nguyen, M Saffarian, CC Smith, EK Holder… - Interventional Pain …, 2023 - Elsevier
This series of FactFinders presents a brief summary of the evidence and outlines
recommendations to improve our understanding and management of several potential …

Medical Concerns in Orthobiologics Procedures

PC Yeh, P Jayaram - Physical Medicine and Rehabilitation …, 2023 - pmr.theclinics.com
Orthobiologics have shown immense treatment potential in many medical fields including
sports medicine, musculoskeletal disorders, and pain management, as well as in plastic …

[HTML][HTML] Platelet-derived biomaterials exert chondroprotective and chondroregenerative effects on diabetes mellitus-induced intervertebral disc degeneration

WC Lo, CC Chang, CH Chan, AK Singh, YH Deng… - Life, 2021 - mdpi.com
Complications of diabetes mellitus (DM) range from acute to chronic conditions, leading to
multiorgan disorders such as nephropathy, retinopathy, and neuropathy. However, little is …

[PDF][PDF] Intradiscal Leukocyte Rich Platelet Rich Plasma for Degenerative Disc Disease

GE Lutz - Physical Medicine and Rehabilitation Clinics of North …, 2023 - binasss.sa.cr
If we could choose a single non-fatal medical condition to find a better solution that would
make the greatest impact on global health it would be a solution for degenerative disc …

[PDF][PDF] North American Spine Society Journal (NASSJ)

J Schol, D Sakai - academia.edu
abstract Background: Intervertebral disc (IVD) degeneration is one of the primary causes of
low back pain (LBP) and despite a prominent prevalence, present treatment options remain …

[HTML][HTML] The Alien Abduction Model of DDD: Why Cellular Drug Trial Results Have Been Underwhelming

C Centeno - regenexx.com
Let's say that you're sleeping one night and get awoken by an alien in your bedroom who
takes you back to the mothership for experiments on your low back. That's pretty much what …