Does Bone Morphogenetic Protein Use Reduce Pseudarthrosis Rates in Single-Level Transforaminal Lumbar Interbody Fusion Surgeries?

J Zhong, J Tareen, K Ashayeri, C Leon… - International Journal of …, 2024 - ijssurgery.com
Background Recombinant human bone morphogenetic protein 2 (rhBMP-2, or BMP for
short) is a popular biological product used in spine surgeries to promote fusion and avoid …

P133. Does bone morphogenic protein (BMP) use reduce pseudoarthrosis rates in single-level TLIF surgeries?

J Zhong, J Tareen, K Ashayeri, C Leon, E Balouch… - The Spine Journal, 2020 - Elsevier
BACKGROUND CONTEXT Recombinant human bone morphogenetic protein 2 (rhBMP-2)
is a popular biologic product used in transforaminal lumbar interbody fusion (TLIF) surgeries …

Bone Morphogenetic Protein in Anterior Lumbar Interbody Fusions: A Propensity-Matched Medicare Outcome Analysis

SI Khalid, RS Nunna, RM Shanker… - International Journal of …, 2022 - ijssurgery.com
Background Bone morphogenetic protein (BMP) is a costly agent commonly used in spine
surgery. Its effectiveness and complication profile have never been studied in a large …

Clinical sequelae after rhBMP-2 use in a minimally invasive transforaminal lumbar interbody fusion

K Singh, SV Nandyala, A Marquez-Lara, TD Cha… - The Spine Journal, 2013 - Elsevier
Background context Recent reports of postoperative radiculitis, bone osteolysis, and
symptomatic ectopic bone formation after recombinant human bone morphogenetic protein …

Bone Morphogenetic Protein in Anterior Lumbar Interbody Fusions: A Propensity-Matched Medicare Outcome Analysis

I Fusions - 2022 - ijssurgery.com
Background: Bone morphogenetic protein (BMP) is a costly agent commonly used in spine
surgery. Its effectiveness and complication profile have never been studied in a large …

Transforaminal lumbar interbody fusion with rhBMP-2 in spinal deformity, spondylolisthesis, and degenerative disease—part 2: BMP dosage–related complications …

DG Crandall, J Revella, J Patterson, E Huish, M Chang… - Spine, 2013 - journals.lww.com
Study Design. Retrospective review of prospectively collected data. Objective. Without
industry funding, the study evaluated short-and long-term complications related to off-label …

Evaluation of heterotopic ossification after using recombinant human bone morphogenetic protein–2 in transforaminal lumbar interbody fusion: A computed …

S Niu, AT Anastasio, RR Faraj… - Global Spine …, 2020 - journals.sagepub.com
Study Design: Retrospective cohort study. Objectives: Reported incidences and
complications of heterotopic ossification (HO) after using recombinant human bone …

Pseudarthrosis following lumbar interbody fusion using bone morphogenetic protein-2: intraoperative and histopathologic findings

PG Whang, BJ O'Hara, J Ratliff, A Sharan… - …, 2011 - journals.healio.com
Bone morphogenetic proteins (BMPs) are known to induce bone formation by stimulating the
osteoblastic differentiation of pluripotential stem cells. 1 The genes for several of these …

Comparison of transforaminal lumbar interbody fusion outcomes in patients receiving rhBMP-2 versus autograft

TR Khan, KR Pearce, SJ McAnany, CM Peters… - The Spine Journal, 2018 - Elsevier
Abstract Background Context Recombinant human bone morphogenetic protein 2 (rhBMP-
2) plays a pivotal role in complex spine surgery. Despite its limited approval, the off-label …

Effectiveness and safety of recombinant human bone morphogenetic protein-2 versus local bone graft in primary lumbar interbody fusions

CL Adams, K Ogden, IK Robertson, S Broadhurst… - Spine, 2014 - journals.lww.com
Study Design. Retrospective cohort study. Objective. To compare clinical outcomes, fusion
rates, and rates of complications in posterior lumbar interbody fusions (PLIFs) and …