Background: Intervertebral disc disease (IDD) is responsible for a large portion of back pain
with historically suboptimal treatments for long-term improvement. IDD pathogenesis is …

Background: Chronic low back pain is one of the most common causes of disability, affecting
more than 600 million people worldwide with major social and economic costs. Current …

Is There Clinical Improvement Associated with Saline Injection for Discogenic Low Back Pain:
Comparison of RCTs - The Spine Journal Skip to Main Content Advertisement The Spine …

Study Design: Post hoc comparison using single-site data from 4 multicenter randomized
controlled trials. Objectives: Discogenic back pain is associated with significant morbidity …

Background Chronic low back pain is one of the most common causes of disability, affecting
more than 600 million people worldwide with major social and economic costs. Current …

Low back pain (LBP) is a common clinical problem and a major cause of physical disability,
imposing a prominent socioeconomic burden. Intervertebral disc degeneration (IDD) has …

ABSTRACT BACKGROUND CONTEXT There are limited treatments for discogenic low back
pain. Intradiscal injections of biologic agents such as platelet-rich plasma (PRP) or stem …

BACKGROUND CONTEXT: Percutaneous intradiscal therapies are gaining popularity as a
regenerative treatment option for spinal disc degeneration. The risks, benefits, and possible …

Specific clinical diagnostic criteria have established a consensus for defining patients with
lumbar discogenic pain. However, if conservative medical management fails, these patients …

Commentary: Does needle injection cause disc degeneration? News in the continuing debate
regarding pathophysiology associated with intradiscal injections - ScienceDirect Skip to main …