Trends in the use of bone morphogenetic protein–2 in adult spinal deformity surgery: a 10-year analysis of 54 054 patients

RDLG Ramos, JO Nakhla, N Bhashyam… - International Journal of …, 2018 - ijssurgery.com
ABSTRACT Background: Bone morphogenetic protein–2 (BMP-2) is an available bone graft
option in spinal fusion surgery. The purpose of this study is to investigate the trends of BMP …

Recombinant human bone morphogenetic protein–2 use in adult spinal deformity surgery: comparative analysis and healthcare utilization at 24 months' follow-up

N Dietz, M Sharma, M Kelly… - Global Spine …, 2022 - journals.sagepub.com
Study Design: Retrospective cohort study. Objective: Recombinant human bone
morphogenetic protein–2 (rhBMP-2) is used to achieve fusion in adult spinal deformity …

The rise and fall of bone morphogenetic protein 2 throughout the United States

AM Beschloss, CM DiCindio, JS Lombardi… - Clinical spine …, 2022 - journals.lww.com
Study Design: Retrospective Database Study. Objective: Investigate utilization of bone
morphogenetic protein (BMP-2) between 2004 and 2014. Summary of Background Data …

The Use of Bone Morphogenetic Protein 2 (BMP-2) in Spine Surgery: Is It Valuable?

L Fernandez, A Petrizzo - Bulletin of the NYU Hospital for Joint …, 2023 - search.proquest.com
Background: Bone morphogenetic protein 2 (BMP-2) is one of the most widely used
biologics in spine surgery. Its osteoinductive properties have been shown since its inception …

Does recombinant human bone morphogenetic protein-2 use in adult spinal deformity increase complications and are complications associated with location of …

S Bess, BG Line, V Lafage, F Schwab, CI Shaffrey… - Spine, 2014 - journals.lww.com
Study Design. Multicenter, prospective analysis of consecutive patients with adult spinal
deformity (ASD). Objective. Evaluate complications associated with recombinant human …

Use of recombinant bone morphogenetic protein is associated with reduced risk of reoperation after spine fusion for adult spinal deformity

JC Paul, BS Lonner, S Vira, ID Kaye, TJ Errico - Spine, 2016 - journals.lww.com
Study Design. Retrospective review. Objective. This study follows the inpatient-stay
administrative data that were collected for a cohort of thousands of patients who had spine …

Bone morphogenetic protein in adult spinal deformity surgery: a meta-analysis

GW Poorman, CM Jalai, A Boniello, N Worley… - European Spine …, 2017 - Springer
Introduction Since its introduction BMP has been utilized in populations with higher rates of
malunion, such as adult spinal deformity (ASD) patients. Contradictory conclusions exist in …

Epidemiological trends in the utilization of bone morphogenetic protein in spinal fusions from 2002 to 2011

K Singh, SV Nandyala, A Marquez-Lara, SJ Fineberg - Spine, 2014 - journals.lww.com
Study Design. Retrospective database analysis. Objective. A nationwide population-based
database was analyzed to assess the utilization trends of bone morphogenetic protein …

Cost–utility analysis of rhBMP-2 use in adult spinal deformity surgery

A Jain, S Yeramaneni, KM Kebaish, M Raad, JL Gum… - Spine, 2020 - journals.lww.com
Study Design. Economic modeling of data from a multicenter, prospective registry. Objective.
The aim of this study was to analyze the cost utility of recombinant human bone …

Use of bone morphogenetic protein among patients undergoing fusion for degenerative diagnoses in the United States, 2002 to 2012

BI Martin, JD Lurie, ANA Tosteson, RA Deyo… - The Spine Journal, 2015 - Elsevier
Background context Use of bone morphogenetic protein (BMP) as an adjunct to spinal
fusion surgery proliferated after Food and Drug Administration (FDA) approval in 2002 …