Correlation between Modic changes and bacterial infection: a causative study

S Singh, GI Siddhlingeswara, A Rai, RD Iyer… - International Journal of …, 2020 - ijssurgery.com
ABSTRACT Study Design: Prospective nonrandomized study. Objective: Objective of the
study was to ascertain etiological correlation between Modic changes (MC) and bacterial …

Prospective study using anterior approach did not show association between Modic 1 changes and low grade infection in lumbar spine

J Rigal, T Thelen, F Byrne, A Cogniet, L Boissière… - European Spine …, 2016 - Springer
Introduction The modern literature is producing a rapidly growing number of articles which
highlight the relationship between infection and lumbar disc degeneration. However, the …

Letter to the editor concerning “Comment to chronic low back pain, bacterial infection and treatment with antibiotics”

P Fritzell, T Bergström, SGE Andersson… - The Spine …, 2021 - thespinejournalonline.com
We would like to inform all readers that your recently published review, or “personal view,”
as the authors call it,“Antibiotic treatment to patients with chronic low back pain and Modic …

Modic changes in the adjacent vertebrae due to disc material infection with Propionibacterium acnes in patients with lumbar disc herniation

J Aghazadeh, F Salehpour, E Ziaeii, N Javanshir… - European Spine …, 2017 - Springer
Abstract Introduction Modic changes (MCs) in vertebral bones are induced by two
mechanisms of mechanical factors and infection. As Propionibacterium acnes (P. acnes) …

Is low back pain after disc herniation with Modic Type 1 changes a low-grade infection?

M Aebi - European Spine Journal, 2013 - Springer
In this issue of the European Spine Journal we are confronted with new data concerning the
significance of Modic Type 1 changes (MC I) in patients with chronic low back pain. We …

[HTML][HTML] Is the discopathy associated with Modic changes an infectious process? Results from a prospective monocenter study

S Ahmed-Yahia, JW Decousser… - PLoS …, 2019 - journals.plos.org
Background The local infectious origin and the putative role of Cutibacterium acnes (CA) of
a particular subtype of discopathy (Modic 1) are still debated. Purpose To establish the …

Antibiotics should not be used for treating back pain due to Modic changes

PM Udby, P Fritzell, T Bergström, B Jönsson… - Ugeskrift for …, 2020 - europepmc.org
Infection has been proposed as a cause of back pain in individuals with Modic changes.
This review summarises the knowledge on this topic in Scandinavia. A Norwegian …

Pilot analysis of association between gut microbiome and modic changes

MB Freidin, P Wells, M Stalteri… - Orthopaedic …, 2019 - boneandjoint.org.uk
Objective Modic changes (MC) is a form of intervertebral disc degeneration visible as
subchondral and vertebral bone marrow changes on spine magnetic resonance (MR). Their …

Are Modic type 2 disc changes associated with low-grade infections? A pilot study.

L Drago, CL Romanò, R Cecchinato… - Journal of …, 2017 - europepmc.org
Background The aim of this study is to compare intraoperative cultural examination in
patients undergoing elective surgery for low-back pain with Modic 2 changes to patients …

[HTML][HTML] Low back pain patients with Modic type 1 changes exhibit distinct bacterial and non-bacterial subtypes

I Heggli, T Mengis, CJ Laux, L Opitz, N Herger… - … and Cartilage Open, 2024 - Elsevier
Objectives Modic type 1 changes (MC1) are vertebral endplate bone marrow (BM) lesions
observed on magnetic resonance images in sub-populations of chronic low back pain …