Background Autologous bone grafts, sourced from the iliac crest, are the gold standard for
bone substitution in spine surgery. However, harvesting autografts increases the risk of …

Spine fusion is a tool used in the treatment of spine trauma, tumors, and degenerative
disorders. Poor outcomes related to failure of fusion, however, have directed the interests of …

Bone grafting has been uniquely practiced since the early 1600s. Historically, bone grafting
includes autologous bone, a variety of allograft bone, and synthetic based-materials utilized …

Currently, a number of bone grafting materials are available in the clinical setting to enhance
bone regeneration, varying from autologous bone to several bone graft substitutes. Although …

Bone grafting materials are the core element of spine fusion, providing the environment for
solid bone formation between two vertebrae. Ideal bone graft is osteoconductive …

Arthrodesis of the spine is the preferred surgical treatment for various types of spinal
pathology, including deformity, instability and degenerative diseases. In addition to …

With the current advances in spinal surgery, an understanding of the precise biological
mechanism of each bone substitute is necessary for inducing successful spinal fusion. In this …

Bone grafting is a prerequisite to obtaining a solid spinal fusion. Bone grafting can also be
used for reconstruction of spinal defects caused by infection, trauma, or tumors. Autogenous …

Autologous bone graft (autograft) is defined as bone graft material harvested from the host. It
can either be taken locally from the surgical site or from a distant donor site. Bone graft …

Study Design: This was a narrative review. Objective: This review discusses our current
knowledge regarding cellular-based allografts while highlighting the key gaps in the …