@article {Gon{\c c}alves Barsotti8085, author = {Carlos Eduardo Gon{\c c}alves Barsotti and R{\'e}jelos Charles Aguiar Lira and Rodrigo Mantelatto Andrade and Alexandre Penna Torini and Ana Paula Ribeiro}, title = {L5 Radiculopathy After Formal Reduction of High-Grade SDSG Type 5 and 6 L5-S1 Isthmic Spondylolisthesis with 2-Year Follow-Up}, elocation-id = {8085}, year = {2021}, doi = {10.14444/8085}, publisher = {International Journal of Spine Surgery}, abstract = {Background Surgery is the main treatment for patients with high-grade L5-S1 isthmic spondylolisthesis, which can result in neurologic complications, but little is known about its clinical course. The present study evaluated the presence of L5 radiculopathy in high-grade L5-S1 spondylolisthesis in adults in pre- and postoperative periods and after a 2-year follow-up.Methods A series of 16 patients who underwent reduction and instrumented fusion for high-grade 5 and 6 spondylolisthesis between 2018 and 2019 were retrospectively evaluated in the pre- and postoperative periods as well as after 6 weeks, 3 months, 6 months, and 1 and 2 years of follow-up. Clinical and surgical data on possible neurological complications of L5 radiculopathy were prospectively collected.Results The age was 20.1 {\textpm} 12.0 years, and preoperative L5-S1 slip was 89.0\%. Five patients presented motor deficit in the preoperative period. In the immediate postoperative period, 9 patients (56\%) experienced motor deficits or worsening of the preoperative condition. At the 6-week follow-up, only 1 patient showed resolution of the motor deficit. Three patients presented healed motor deficits after 3 months, and 1 patient demonstrated a healed L5 motor radiculopathy after 6 months. At the 1-year follow-up, only 1 patient exhibited an L5 radiculopathy motor deficit, and at the 2-year follow-up, none of the patients exhibited an L5 radiculopathy motor deficit.Conclusion L5 radiculopathy was frequent in the preoperative period and increased after reduction and instrumented fusion of high-grade L5-S1 spondylolisthesis in the postoperative period and in the 6-week follow-up. Three and 6 months after the surgery, there were consecutive motor improvements. After 2 years of follow-up, no patients showed neurological deficit of L5 radiculopathy.Level of Evidence 2.Clinical Relevance This is the first study reporting a reduction in complications of L5 neurological motor deficit over a 2-year follow-up in high-grade L5-S1 spondylolisthesis in young adults.}, issn = {2211-4599}, URL = {https://www.ijssurgery.com/content/early/2021/07/16/8085}, eprint = {https://www.ijssurgery.com/content/early/2021/07/16/8085.full.pdf}, journal = {International Journal of Spine Surgery} }