RT Journal Article
SR Electronic
T1 Does Cervical Spondylolisthesis Influence Patient-Reported Outcomes After Anterior Cervical Discectomy and Fusion Surgery?
JF International Journal of Spine Surgery
JO Int J Spine Surg
FD International Society for the Advancement of Spine Surgery
SP 1161
OP 1166
DO 10.14444/8147
VO 15
IS 6
A1 Dhruv K.C. Goyal
A1 Justin D. Stull
A1 Srikanth N. Divi
A1 John J. Mangan
A1 William K. Conaway
A1 Landon Foulger
A1 Kristen J. Nicholson
A1 Christopher K. Kepler
A1 Alan S. Hilibrand
A1 Barrett I. Woods
A1 Kristen E. Radcliff
A1 D. Greg Anderson
A1 Mark F. Kurd
A1 Jeffrey A. Rihn
A1 I. David Kaye
A1 Alexander R. Vaccaro
A1 Gregory D. Schroeder
YR 2021
UL http://ijssurgery.com//content/15/6/1161.abstract
AB Background No prior work has explored whether the presence of degenerative spondylolisthesis impacts patient-reported outcome measurements (PROMs) after an anterior cervical discectomy and fusion (ACDF); therefore, the goal of the current study was to determine whether the presence of a spondylolisthesis affects PROMs after an ACDF.Methods A retrospective cohort study was conducted on patients over the age of 18 who underwent a 1- or 2-level ACDF. All patients received preoperative standing lateral x-rays and were placed into 1 of 2 groups based on the presence of cervical spondylolisthesis from C2-T1: (1) no spondylolisthesis (NS) group or (2) spondylolisthesis (S) group. Preoperative, postoperative, and delta (postoperative minus preoperative) were recorded and compared between groups via univariate and multivariate analysis. Outcomes reported were the Physical Component Scores of the Short Form-12 (PCS-12), the Mental Component Scores of the Short Form-12 (MCS-12), the Neck Disability Index (NDI), and visual analog scale (VAS) Arm/Neck.Results A total of 202 patients were included in the final analysis with 154 in the NS group and 48 in the S group. Both patient cohorts reported significant postoperative improvement in PCS-12, NDI, and VAS Arm/Neck. When comparing outcome scores between groups, only MCS-12 delta scores were different between groups, with the S group exhibiting a greater mean delta score (8.3 vs 1.3, P = 0.024) than the NS group after ACDF. Multiple linear regression analysis indicated having spondylolisthesis at baseline was a significant predictor of greater change in MCS-12 than the NS group (β = 4.841; 95% CI, 0.876, 8.805; P = 0.017).Conclusion Both groups demonstrated significant postoperative improvement in PCS-12, NDI, or VAS Neck/Arm pain scores with no significant differences between groups. Patients with spondylolisthesis were found to have significantly greater improvement scores in MCS-12 scoring than those without spondylolisthesis after ACDF surgery.