PT - JOURNAL ARTICLE AU - Patel, Vikas V. AU - Billys, James AU - Okonkwo, David O. AU - He, David Y. AU - Ryaby, James T. AU - Radcliff, Kris TI - Three- and 4-Level Lumbar Arthrodesis Using Adjunctive Pulsed Electromagnetic Field Stimulation: A Multicenter Retrospective Evaluation of Fusion Rates and a Review of the Literature AID - 10.14444/8031 DP - 2021 Apr 01 TA - International Journal of Spine Surgery PG - 228--233 VI - 15 IP - 2 4099 - https://www.ijssurgery.com/content/15/2/228.short 4100 - https://www.ijssurgery.com/content/15/2/228.full SO - Int J Spine Surg2021 Apr 01; 15 AB - Background: The incidence of 3- and 4-level lumbar arthrodesis is rising due to an aging population, and fusion rates affect clinical success in this population. Pulsed electromagnetic field (PEMF) stimulation is used as an adjunct to increase fusion rates following multilevel arthrodesis. The purpose of the study was to evaluate the fusion rates for subjects who underwent 3- and 4-level lumbar interbody arthrodesis following PEMF treatment.Methods: In this retrospective, multicenter study, patient charts that listed 3- or 4-level lumbar arthrodesis with adjunctive use of a PEMF device were evaluated. Inclusion criteria included patients who were diagnosed with lumbar degenerative disease, spinal stenosis, and/or spondylolisthesis (grade 1 or 2). A radiographic evaluation of fusion status was performed at 12 months by the treating physicians. Fusion rates were stratified by graft material, surgical interbody approach, and certain clinical risk factors for pseudoarthrosis.Results: A total of 55 patients were identified who had a 12-month follow-up. The radiographic fusion rate was 92.7% (51 patients) at 12 months. There were no significant differences in fusion rates for patients treated with allograft or autograft, for patients with different interbody approaches, or for those with or without certain clinical risk factors.Conclusions: With modern fusion techniques and PEMF, the overall fusion rate was high following 3- and 4-level lumbar arthrodesis.Level of Evidence: 4.Clinical Relevance: PEMF may be a useful adjunct for treatment of patients with surgical risk factors, such as multilevel arthrodesis, and clinical risk factors.