RT Journal Article
SR Electronic
T1 Synthetic Bone Graft Materials in Spine Fusion: Current Evidence and Future Trends
JF International Journal of Spine Surgery
JO Int J Spine Surg
FD International Society for the Advancement of Spine Surgery
SP 104
OP 112
DO 10.14444/8058
VO 15
IS s1
A1 Mark A. Plantz
A1 Erik B. Gerlach
A1 Wellington K. Hsu
YR 2021
UL http://ijssurgery.com//content/15/s1/104.abstract
AB Historically, iliac crest bone autograft has been considered the gold standard bone graft substitute for spinal fusion. However, the significant morbidity associated with harvesting procedures has influenced decision-making and practice patterns. To minimize these side effects, many clinicians have pursued the use of bone graft extenders to minimize the amount of autograft required for fusion in certain applications. Synthetic materials, including a variety of ceramic compounds, are a class that has been studied extensively as bone graft extenders. These have been used in combination with a wide array of other biomaterials and investigated in a variety of different spine fusion procedures. This review will summarize the current evidence of different synthetic materials in various spinal fusion procedures and discuss the future of novel synthetics.