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Anterior lumbar fusion using a hybrid interbody graft

A preliminary radiographic report

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Summary

This is a radiographic report of 40 patients (20 men, 20 women) who underwent anterior lumbar interbody fusions (73 levels) utilizing a “hybrid” interbody graft composed of femoral cortical allograft (FCA) bone and iliac crest cancellous autograft bone. The average age at surgery was 38 years (range 17–64 years), and follow-up averaged 1.4 years (range 1.0–2.4 years). Nineteen of the patients had undergone previous lumbar surgery. Thirty-two patients (63 levels) underwent anterior fusion combined with some type of posterior fixation, and eight patients (10 levels) had no posterior fixation. Types of posterior fixation included: for 20 patients (36 levels) Steffee variable screw placement fixation, for 10 patients (23 levels) translaminar facet screws (TFS), for 1 patient (3 levels) Knodt rods and for 1 patient (1 level) facet screws. Based on the persistence of lucent lines at the graft-host interface, three patients (one level each) were felt to have non-unions at their latest follow-ups at 1.4, 1.5 and 2.0 years, respectively. Two of these patients had no posterior fixation, and the other had TFS fixation. The overall fusion rate was 96% (70 of 73 levels). The fusion rate for all levels treated with posterior fixation was 98% compared with 75% for those without fixation. Intervertebral disc heights (IVDH) were measured on all films and corrected for magnification with computer assistance. On average, the IVDH was increased postoperatively but returned to preoperative values at follow-up. IVDH loss was independent of the type of instrumentation used. No complications arose from the use of the hybrid graft. Incorporation of the allograft portion of the graft is slow and was felt to be complete in only 7 of the 73 levels at follow-up. We conclude that the hybrid interbody graft technique is a safe and reliable method for performing anterior lumbar interbody fusions and should be combined with some type of posterior fixation. Long-term follow-up will be required to assess the behaviour of the allograft until incorporation is complete.

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References

  1. Allen DG, Lavoie GJ, Rudan JF, Gross AE (1991) The use of allograft bone in revision total hip arthroplasty. In: Freidlander GE, Goldberg VM (eds) Bone and cartilage allografts: biology and clinical applications. American Academy of Orthopaedic Surgeons, pp 255–278

  2. Aurori BF, Weirman RJ, Lowell HA, Nadel CI, Parsons JR (1985) Pseudarthrosis after spinal fusion for scoliosis: a comparison of autogenic and allogenic bone grafts. Clin Orthop 199: 153–158

    PubMed  Google Scholar 

  3. Burns BH (1933) An operation for spondylolisthesis. Lancet 1: 1233

    Article  Google Scholar 

  4. Calandruccio RA, Benton BF (1964) Anterior lumbar fusion. Clin Orthop 35: 63–68

    PubMed  CAS  Google Scholar 

  5. Capner N (1932) Spondylolithesis. Br J Surg 19: 374–386

    Google Scholar 

  6. Crock HV (1982) Anterior lumbar interbody fusion, indications for its use and notes on surgical technique. Clin Orthop 165: 157–163

    PubMed  Google Scholar 

  7. Dennis S, Watkins R, Landaker S, Dillin W, Springer D (1989) Comparison of disc space heights after anterior lumbar interbody fusion. Spine 14: 876–878

    PubMed  CAS  Google Scholar 

  8. Dwyer AF, Newton NC, Sherwood AA (1969) An anterior approach to scoliosis — a preliminary report. Clin Orthop 62: 192–202

    PubMed  CAS  Google Scholar 

  9. Fairbank JCT, Couper J, Davies JB, O'Brien JP (1990) The Oswestry low back pain disability questionnaire. Physiotherapy 66: 271–273

    Google Scholar 

  10. Flynn JC, Hoque MA (1979) Anterior fusion of the lumbar spine, end-result study with long-term follow-up. J Bone Joint Surg [Am] 61: 1143–1150

    CAS  Google Scholar 

  11. Fraser RD, Gogan WJ (1982) A wide muscle splitting approach to the lumbosacral spine. J Bone Joint Surg [Br] 64: 44–47

    CAS  Google Scholar 

  12. Freebody D, Bendall R, Taylor RD (1971) Anterior transperitoneal lumbar fusion. J Bone Joint Surg [Br] 53: 617–627

    CAS  Google Scholar 

  13. Fujimaki A, Crock HV, Bedbrook GM (1982) The results of 150 anterior lumbar fusion operations performed by two surgeons in Australia. Clin Orthop 165: 164–167

    PubMed  Google Scholar 

  14. Goldberg VM, Stevens S (1987) Natural history of autografts and allografts. Clin Orthop 225: 7–16

    PubMed  Google Scholar 

  15. Harmon PH (1963) Amerior excision and vertebral body fusion for intervertebral disc syndromes of the lower lumbar spine. Three to five year results in 244 cases. Clin Orthop 26: 107–127

    PubMed  CAS  Google Scholar 

  16. Herron LD, Newman MH (1989) The failure of ethylene oxide gas-sterilized freeze-dried bone graft for thoracic and lumbar spinal fusion. Spine 14: 496–500

    PubMed  CAS  Google Scholar 

  17. Hoover NW (1968) Methods of lumbar spine fusion. J Bone Joint Surg [Am] 50: 194–210

    Google Scholar 

  18. Jasty DG, Harris WH (1987) Total hip reconstruction using frozen femoral head allograft in patients with acetabular bone loss. Clin Orthop 18: 291–299

    CAS  Google Scholar 

  19. Kaneda K, Abumi K, Fujiya M (1984) Burst fractures with neurologic deficits of the thoracolumbar-lumbar spine. Spine 9: 788–795

    PubMed  CAS  Google Scholar 

  20. Kozak JA, O'Brien JP (1990) Simultaneous combined anterior and posterior fusion: an independent analysis of a treatment for the disabled low back patient. Spine 15: 322–328

    PubMed  CAS  Google Scholar 

  21. Lane JD Jr, Moore ES Jr (1948) Transperitoneal approach to the intervertebral disc in the lumbar area. Ann Surg 127: 537–551

    CAS  Google Scholar 

  22. Malinin TI, Brown MD (1981) Bone grafts in spinal surgery. Clin Orthop 154: 68–73

    PubMed  Google Scholar 

  23. Mankin HJ, Gebhardt MC, Tomford WW (1987) The use of frozen cadaveric allografts in the management of patients with bone tumors of the extremities. Orthop Clin North Am 18: 275–289

    PubMed  CAS  Google Scholar 

  24. McCarthy RE, Richard DP, Morrissy RT, Hough AJ (1986) Allograft bone in spinal fusion for paralytic scoliosis. J Bone Joint Surg [Am] 68: 370–375

    CAS  Google Scholar 

  25. Mizutani H, Urist MR (1982) The nature of bone morphogenic protein (BMP) fraction derived from bovine bone matrix gelatin. Clin Orthop 171: 213–223

    PubMed  CAS  Google Scholar 

  26. Montesano PX, Magerl FP, Jacobs RR, Jackson RP Rauschning W (1988) Translaminar facet screws. Orthopaedics 11: 1393–1397

    CAS  Google Scholar 

  27. Nasca RJ, Whelchel JD (1987) Use of cryopreserved bone in spinal surgery. Spine 12: 222–227

    Article  PubMed  CAS  Google Scholar 

  28. O'Brien JP, Holte DC (1992) Simultaneous combined anterior and posterior fusion. A review of its concept and 10 years of refinement of the technique: a solution for the patient with severe back and leg pain. Eur Spine J 1: 2–6

    Article  PubMed  Google Scholar 

  29. O'Brien JP, Dawson MHO, Heard CW, Momberger G, Speck G, Weatherly CR (1986) Simultaneous combined anterior and posterior fusion. A surgical solution for failed spinal surgery with a brief review of the first 150 patients. Clin Orthop 203: 191–195

    PubMed  Google Scholar 

  30. Stauffer RN, Coventry MB (1972) Anterior interbody lumbar spine fusion for low back pain. J Bone Joint Surg [Am] 54: 756–768

    CAS  Google Scholar 

  31. Urist MR, Dawson E (1981) Intertransverse process fusion with the aid of chemisterilized autolyzed antigen-extracted allogenic (AAA) bone. Clin Orthop 154: 97–113

    PubMed  Google Scholar 

  32. Zielke K, Stundat R, Beaujean F (1976) Ventrale derotationsspondylodese. Vorläufiger Ergebnisbericht über 26 operierte Fälle. Arch Orthop Unfallchir 85: 257–277

    Article  PubMed  CAS  Google Scholar 

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Holte, D.C., O'Brien, J.P. & Renton, P. Anterior lumbar fusion using a hybrid interbody graft. Eur Spine J 3, 32–38 (1994). https://doi.org/10.1007/BF02428314

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