Biochimica et Biophysica Acta (BBA) - Protein Structure
Quantitative analysis of types I and II collagens in human intervertebral discs at various ages
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The pathological mechanisms of circRNAs in mediating intervertebral disc degeneration
2023, Non-coding RNA ResearchA multiscale investigation into the role of collagen-hyaluronan interface shear on the mechanical behaviour of collagen fibers in annulus fibrosus – Molecular dynamics-cohesive finite element-based study
2023, Journal of the Mechanical Behavior of Biomedical MaterialsA novel bio-inspired hydrogel-based lattice structure to mechanically mimic human annulus fibrosus: A finite element study
2021, International Journal of Mechanical SciencesCitation Excerpt :The intervertebral disc annulus fibrosus is known to be highly heterogeneous with regional dependent microstructure/properties relationships [14–18]. The annulus mechanics changes between the different radial and circumferential regions of the same disc due to the different local quantities of the constituent elements (collagen fibers, proteoglycans, water) and the collagen organization along with interactions with the surrounding physiological medium [14–15,18]. Especially, the transversal strains have been proved recently to show unusual behavior with negative Poisson's ratios in the disc radial direction and Poisson's ratios superior to 0.5 in the disc axial direction under a circumferential loading of the annulus fibrosus [19–22].
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Present address: Harvard Medical School, Orthopaedic Research Laboratories, Children's Hospital Medical Center, 300 Longwood Avenue, Boston, Massachusetts 02115, U.S.A.