Biochemical changes in intervertebral disc degeneration
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Cited by (272)
Current applications of biomolecules in biomedical engineering
2023, Handbook of Biomolecules: Fundamentals, Properties and ApplicationsEffect of intervertebral disc degeneration on mechanical and electric signals at the interface between disc and vertebra
2020, Journal of BiomechanicsCitation Excerpt :It has been found that the electric potential in the disc changes with the alteration of the fixed charge density of the disc (Yao and Gu, 2007). Since the fixed charge density decreases with the disc degeneration (Antoniou et al., 1996; Iatridis et al., 2007; Lyons et al., 1981; Urban and Maroudas, 1979), it is important to know how the electric potential at the disc-vertebra interface varies with the disc degeneration. The objective of this study was to numerically investigate the changes in mechanical and electrical signals on the disc-vertebra interface with disc degeneration.
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