Outcome of excisional surgeries for the patients with spinal metastases

Eur Spine J. 2009 Oct;18(10):1423-30. doi: 10.1007/s00586-009-1111-9. Epub 2009 Aug 5.

Abstract

To evaluate the outcome of the excisional surgeries (en bloc/debulking) in spinal metastatic treatment in 10 years. A total of 131 patients (134 lesions) with spinal metastases were studied. The postoperative survival time and the local recurrence rate were calculated statistically. The comparison of the two procedures on the survival time, local recurrence rate, and neurologic change were made. The median survival time of the en bloc surgery and the debulking surgery was 40.93 and 24.73 months, respectively, with no significant difference. The significant difference was shown in the local recurrence rate comparison, but not in neurological change comparison. 19.85% patients combined with surgical complications. The en bloc surgery can achieve a lower local recurrence rate than the debulking surgery, while was similar in survival outcome, neurological salvage, and incidence of complications. The risk of the excisional surgeries is high, however, good outcomes could be expected.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Combined Modality Therapy / instrumentation
  • Combined Modality Therapy / methods
  • Drug Therapy
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / mortality
  • Neoplasm Recurrence, Local / prevention & control
  • Neoplasm Recurrence, Local / surgery
  • Neurosurgical Procedures / instrumentation
  • Neurosurgical Procedures / methods*
  • Neurosurgical Procedures / mortality
  • Outcome Assessment, Health Care / methods
  • Postoperative Complications / epidemiology
  • Prognosis
  • Radiography
  • Radiotherapy
  • Risk Assessment
  • Spinal Fusion / methods
  • Spinal Neoplasms / mortality
  • Spinal Neoplasms / secondary*
  • Spinal Neoplasms / surgery*
  • Spine / diagnostic imaging
  • Spine / pathology*
  • Spine / surgery*
  • Survival Rate
  • Treatment Outcome
  • Vertebroplasty / methods
  • Young Adult