The anterior stand-alone approach (ASAA) during the acute phase of spondylodiscitis: results in 40 consecutively treated patients

Eur Spine J. 2012 May;21 Suppl 1(Suppl 1):S75-82. doi: 10.1007/s00586-012-2238-7. Epub 2012 Mar 10.

Abstract

Purpose: Spondylodiscitis mainly affects the anterior part of the spine. In this paper, we retrospectively analyze our experience with the anterior stand-alone approach (ASAA) in the treatment of spinal infections.

Methods: Forty consecutive patients with severe spondylodiscitis underwent the ASAA during the acute infective phase. Treatment consisted of disease debridement, vertebral body reconstruction using titanium expandable prostheses and anterior fixation.

Results: There was neither mortality nor major morbidity. Successful arthrodesis was achieved in 39 out of 40 patients who remained disease free throughout the follow-up period. Six months after treatment, one patient experienced pseudarthrosis and required supplemented posterior spinal fixation for vertebral instability. However, adequate arthrodesis was eventually obtained even in this patient.

Conclusions: ASAA with spine reconstruction using synthetic materials during the acute infection phase was safe and effective. The infections were rapidly defeated, the patients were allowed to stand up early after the procedure and the length of hospital stay was significantly reduced.

MeSH terms

  • Acute Disease
  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents / therapeutic use
  • Arthrodesis / instrumentation*
  • Arthrodesis / methods*
  • Cervical Vertebrae / pathology
  • Cervical Vertebrae / surgery
  • Debridement*
  • Discitis / drug therapy
  • Discitis / pathology
  • Discitis / surgery*
  • Female
  • Follow-Up Studies
  • Humans
  • Lumbar Vertebrae / pathology
  • Lumbar Vertebrae / surgery
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Prostheses and Implants*
  • Retrospective Studies
  • Thoracic Vertebrae / pathology
  • Thoracic Vertebrae / surgery
  • Titanium
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Titanium