User profiles for Aladine A. Elsamadicy
Aladine ElsamadicyDepartment of Neurosurgery, Yale School of Medicine Verified email at yale.edu Cited by 4411 |
[HTML][HTML] Leptomeningeal disease: current diagnostic and therapeutic strategies
…, T Ejikeme, P Chongsathidkiet, AA Elsamadicy… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Leptomeningeal disease has become increasingly prevalent as novel therapeutic interventions
extend the survival of cancer patients. Although a majority of leptomeningeal spread …
extend the survival of cancer patients. Although a majority of leptomeningeal spread …
Prevalence and cost analysis of complex regional pain syndrome (CRPS): a role for neuromodulation
Objective The diagnosis and treatment of complex regional pain syndrome (CRPS) is
challenging and there is a paucity of data describing its overall cost burden and quantifying its …
challenging and there is a paucity of data describing its overall cost burden and quantifying its …
PTEN mutations in autism spectrum disorder and congenital hydrocephalus: developmental pleiotropy and therapeutic targets
The lack of effective treatments for autism spectrum disorder (ASD) and congenital
hydrocephalus (CH) reflects the limited understanding of the biology underlying these common …
hydrocephalus (CH) reflects the limited understanding of the biology underlying these common …
Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors
…, X Cui, SH Farber, K Woroniecka, AA Elsamadicy… - Nature medicine, 2018 - nature.com
T cell dysfunction contributes to tumor immune escape in patients with cancer and is
particularly severe amidst glioblastoma (GBM). Among other defects, T cell lymphopenia is …
particularly severe amidst glioblastoma (GBM). Among other defects, T cell lymphopenia is …
T-cell exhaustion signatures vary with tumor type and are severe in glioblastoma
…, H Kemeny, C Dechant, SH Farber, AA Elsamadicy… - Clinical Cancer …, 2018 - AACR
Purpose: T-cell dysfunction is a hallmark of glioblastoma (GBM). Although anergy and
tolerance have been well characterized, T-cell exhaustion remains relatively unexplored. …
tolerance have been well characterized, T-cell exhaustion remains relatively unexplored. …
Early ambulation decreases length of hospital stay, perioperative complications and improves functional outcomes in elderly patients undergoing surgery for …
O Adogwa, AA Elsamadicy, J Fialkoff, J Cheng… - Spine, 2017 - journals.lww.com
Study Design. Ambispective cohort review. Objective. To examine the effects of early mobilization
on patient outcomes, complications profile, and 30-day readmission rates. Summary of …
on patient outcomes, complications profile, and 30-day readmission rates. Summary of …
Temozolomide lymphodepletion enhances CAR abundance and correlates with antitumor efficacy against established glioblastoma
Adoptive transfer of T cells expressing chimeric antigen receptors (CARs) is an effective
immunotherapy for B-cell malignancies but has failed in some solid tumors clinically. …
immunotherapy for B-cell malignancies but has failed in some solid tumors clinically. …
Andexanet alfa versus 4-factor prothrombin complex concentrate for reversal of factor Xa inhibitors in intracranial hemorrhage
Background/Objective There are limited data on the risks and benefits of using andexanet alfa
(AA) in comparison with four-factor prothrombin complex concentrate (4F-PCC) to reverse …
(AA) in comparison with four-factor prothrombin complex concentrate (4F-PCC) to reverse …
[HTML][HTML] Long-term cost utility of spinal cord stimulation in patients with failed back surgery syndrome
SH Farber, JL Han, AA Elsamadicy, Q Hussaini… - Pain …, 2017 - ncbi.nlm.nih.gov
Background: Failed back surgery syndrome (FBSS) is a cause of significant morbidity for up
to 40% of patients following spine surgery, and is estimated to cost almost $20 billion. …
to 40% of patients following spine surgery, and is estimated to cost almost $20 billion. …
[PDF][PDF] Prevalence of specific types of pain diagnoses in a sample of United States adults
Background: Patients with pain conditions place significant demands on health care services
globally. Health economists have reported the annual economic cost of pain in the United …
globally. Health economists have reported the annual economic cost of pain in the United …