Background. Progressive nephrotoxicity caused by calcineurin inhibitor drugs contributes to
the long-term decline in renal function in kidney transplant patients. Methods. We conducted …

A major challenge for kidney transplantation is balancing the need for immunosuppression
to prevent rejection, while minimizing drug‐induced toxicities. We used DNA microarrays (HG…

We performed a randomized prospective trial comparing calcineurin inhibitor (CNI)-free to
CNI-based immunosuppression to determine the impact on renal function, structure and gene …

BACKGROUND: It is possible, but unproven, that hepatitis C (HCV) infection accelerates
atherosclerosis. We evaluated the hypothesis that donor HCV seropositivity predicts mortality …

Background. We report the 5-year outcomes from a randomized prospective trial in primary
adult renal allograft recipients, designed to evaluate calcineurin inhibitor (CNI)-free …

Class I molecules of human major histocompatibility complex (HLA) are the most important
antigenic system in determining the survival of transfused platelets in alloim-munized patients…

Background A thorough understanding of the biomechanical characteristics of the healthy
human spine is critical in furthering the treatment of spinal pathology. The goal of this study …

Background. Risk factors for death after heart transplantation (Tx) are frequently documented
from multicenter registries. Although this information is helpful, it reflects a whole range of …

This book is an extensively revised version of a dissertation submitted in partial fulfillment of
the requirements for a doctoral degree at Columbia University. Since it was written in the …

Purpose Spinal interbody fusion cages are designed to provide immediate stabilization for
adjoining vertebrae and ideally enable bony ingrowth to achieve successful integration. For …