Osteoarthritis, characterized by the breakdown of articular cartilage in synovial joints, has
long been viewed as the result of 'wear and tear' 1 . Although low-grade inflammation is …

We sequenced the complete 16.5-kb mitochondrial genome (mtDNA) in 15 pancreatic cancer
cell lines and xenografts. Homoplasmic mtDNA somatic mutations and novel variants were …

Background: Spinal cord stimulation is an intervention that has become increasingly popular
due to the growing body of literature showing its effectiveness in treating pain and the …

Tyrosine kinases play a central role in the activation of signal transduction pathways and
cellular responses that mediate the pathogenesis of rheumatoid arthritis. Imatinib mesylate (…

Mesenchymal cell (MC) condensation or the aggregation of MCs precedes chondrocyte
differentiation and is required for subsequent cartilage formation during endochondral …

The immune and coagulation systems are both implicated in the pathogenesis of rheumatoid
arthritis (RA). Plasma carboxypeptidase B (CPB), which is activated by the thrombin/…

Purpose and Experimental Design: The mutational spectrum of MADH4 (DPC4/SMAD4) opens
valuable insights into the functions of this protein that confer its tumor-suppressive nature …

Recently, 4 separate human controlled trials reported that honey appeared to protect from
the effects of radiation-induced oral mucositis formation, a complication of radiation therapy …

Objectives We investigated whether systemic immune‐inflammation index (SII) at diagnosis
can estimate the cross‐sectional high activity and predict the poor outcomes in …

PURPOSE: To enhance the clinician's competence in interpretation of research studies
related to use of honey for wound healing. TARGET AUDIENCE: This continuing education …