Cell-free DNA shed by cancer cells has been shown to be a rich source of putative tumor-specific
biomarkers. Because cell-free DNA from brain and spinal cord tumors cannot usually …

BACKGROUND: Vertebroplasty (VP) and kyphoplasty (KP) are routinely used to treat vertebral
body compression fractures (VCFs) resulting from osteoporosis or vertebral body tumors …

OBJECTIVE: It remains unknown whether aggressive disc removal with curettage or limited
removal of disc fragment alone with little disc invasion provides a better outcome for the …

Object En bloc resection with adequate margins is associated with the highest probability of
long-term tumor control or cure in most cases of primary sacral malignancies. The authors …

✓Symptomatic irreducible basilar invagination has traditionally been approached through a
transoral–transpharyngeal route with resection of the anterior portion of C-1 and the odontoid…

Metastatic epidural spinal cord compression (MESCC) is becoming a more common clinically
encountered entity as advancing systemic antineoplastic treatment modalities improve …

BACKGROUND: Pedicle screws are used to stabilize all 3 columns of the spine, but can be
technically demanding to place. Although intraoperative fluoroscopy and stereotactic-guided …

OBJECTIVE Same-level recurrent lumbar disc herniation complicates outcomes after primary
discectomy in a subset of patients. The health care costs associated with the management …

BACKGROUND: En bloc resection of primary sacral tumors has a demonstrated survival
benefit. Total and high sacral amputations are traditionally performed by using a staged anterior …

Object Advocates of minimally invasive discectomy (MID) have promoted this operation as an
alternative to open discectomy (OD), arguing that there may be less injury to the paraspinal …