Background: This manuscript is a review of the literature investigating the use of
mesenchymal stem cells (MSCs) being applied in the setting of spinal fusion surgery. We …

Study Design: Review of literature. Objectives: This review of literature investigates the
application of mesenchymal stem cells (MSCs) in spinal fusion, highlights potential uses in …

More than 50% of patients complain of postoperative donor site morbidity following iliac
crest bone graft harvest, and recent discoveries have identified adverse outcomes following …

The use of spinal fusion procedures has rapidly augmented over the last decades and
although autogenous bone graft is the “gold standard” for these procedures, alternatives to …

OBJECTIVE Spinal fusion surgery is increasingly common; however, pseudarthrosis
remains a common complication affecting as much as 15% of some patient populations …

Background Spinal fusion is the mainstay treatment for various spinal conditions ranging
from lumbar and cervical stenosis to degenerative spondylolisthesis as well as extensive …

Study Design. Systematic review. Objective. To compare the clinical outcome of cell based
grafts combined with bone extenders to autologous bone grafts. Summary of Background …

For a successful spinal fusion to occur, several vital elements are necessary. They consist of
the presence of the bone-forming cell (osteoblast) or its precursor, the appropriate biological …

Mesenchymal stromal cells (MSCs) have been a promising area of study for regenerative
medicine. These cells can be harvested from bone marrow, adipose tissue, and other areas …

While the use of biologics as adjuncts for spine surgery is growing annually stem cells have
yet to be approved for this clinical application. Stem cells have the unique ability to …