Background Adipose tissue-derived mesenchymal stem cells (AT-MSCs) offer potential as a
therapeutic option for chronic discogenic low back pain (LBP) because of their …

Compression of the spinal cord can result from trauma, cancer, epidural abscess, or epidural
hematoma and can have a variety of clinical manifestations based on the anatomical level …

CONCLUSION: Although longer-term follow-up and investigation are required, this case
demonstrates that a polymer scaffold can be safely implanted into an acutely contused spinal …

Mesenchymal stromal stem cells (MSCs) isolated from adult tissues offer tangible potential for
regenerative medicine, given their feasibility for autologous transplantation. MSC research …

Primary vertebral tumors, although less common than metastases to the spine, make up a
heterogeneous group of neoplasms that can pose diagnostic and treatment challenges. They …

The blood-spinal cord barrier (BSCB) is a specialized protective barrier that regulates the
movement of molecules between blood vessels and the spinal cord parenchyma. Analogous to …

… In this article, Ropper et al present a concise review of the most common locally aggressive
and malignant primary bone tumors. The epidemiology, clinical course, histology, and …

Patients with acute cervical spinal cord injury present complex clinical challenges. These
injuries may result in motor and sensory deficits and also in cardiovascular and respiratory …

Diverse mechanisms including activation of NMDA receptors, microglial activation, reactive
astrogliosis, loss of descending inhibition, and spasticity are responsible for ∼40% of cases …

Back pain is currently the most common musculoskeletal complaint affecting millions of
individuals every year. 1–3 Back pain significantly contributes to patient morbidity and health …