There is an increasing recognition that, in the long term, total joint replacement may be
associated with adverse local and remote tissue responses that are mediated by the degradation …

There has been a resurgence of interest in the use of metal on metal bearings in total hip
arthroplasty. Although the use of metal on metal bearing couples would eliminate or …

In the majority of patients, orthopaedic implants are biocompatible. However, there is an
increasing recognition that, in the long-term, permanent orthopaedic implants may be …

In this study, the local and distant distribution of solid and soluble products of corrosion from
the head and neck junction of modular femoral total hip prosthetic components were …

Metal‐on‐metal bearing couples remain a popular option in total hip arthroplasty and are
the only currently available option for surface replacement arthroplasty. In general, the …

Concentrations of titanium, aluminum, and vanadium were measured in the serum and
urine of patients with titanium alloy cementless primary total knee arthroplasty components. …

We previously reported on the metal ion concentrations of cobalt, chromium, and titanium that
were found in the serum of patients three years after they had undergone primary total hip …

Background: Total hip replacements with metal-on-metal bearings are frequently implanted
in young, active patients. The relationship between patient activity and cobalt and chromium …

In this review, the prospects for using blood, serum, and/or urine metal levels for monitoring
the performance of metal-on-metal hip arthroplasty systems are explored. This approach …

The resurgence of metal-on-metal articulating surfaces for hip arthroplasty has also
heightened concerns about the degree and magnitude of metal particle generation and the …