Structured coculture of stem cells and disc cells prevent disc degeneration in a rat model

AA Allon, N Aurouer, BB Yoo, EC Liebenberg, Z Buser… - The Spine Journal, 2010 - Elsevier
BACKGROUND CONTEXT: Harnessing the potential of stem cells is an important strategy for
regenerative medicine. This study explores the use of bilaminar coculture pellets (BCPs) of …

A Novel Macroporous Polyvinyl Alcohol Scaffold Promotes Chondrocyte Migration and Interface Formation in an In Vitro Cartilage Defect Model

…, F Wanivenhaus, T Chen, HC Hsu, AA Allon… - … Engineering Part A, 2012 - liebertpub.com
Scaffold–cartilage integration is critical for the clinical success of a scaffold used for the
repair of a focal cartilage defect. In this study, a macroporous polyvinyl alcohol (PVA) scaffold …

Augmenting the articular cartilage‐implant interface: Functionalizing with a collagen adhesion protein

AA Allon, KW Ng, S Hammoud… - … Research Part A, 2012 - Wiley Online Library
The lack of integration between implants and articular cartilage is an unsolved problem that
negatively impacts the development of treatments for focal cartilage defects. Many …

Structured bilaminar coculture outperforms stem cells and disc cells in a simulated degenerate disc environment

AA Allon, K Butcher, RA Schneider, JC Lotz - Spine, 2012 - journals.lww.com
Study Design. This study explores the use of bilaminar coculture pellets of mesenchymal stem
cells (MSCs) and nucleus pulposus cells (NPCs) as a cell-based therapy for intervertebral …

Structured coculture of mesenchymal stem cells and disc cells enhances differentiation and proliferation

AA Allon, K Butcher, RA Schneider, JC Lotz - Cells Tissues Organs, 2012 - karger.com
Purpose: During in vivo stem cell differentiation, mature cells often induce the differentiation
of nearby stem cells. Accordingly, prior studies indicate that a randomly mixed coculture can …

Co-culture of adult mesenchymal stem cells and nucleus pulposus cells in bilaminar pellets for intervertebral disc regeneration

AA Allon, RA Schneider, JC Lotz - International Journal of Spine …, 2009 - ijssurgery.com
Background Our goal is to optimize stem cell-based tissue engineering strategies in the
context of the intervertebral disc environment. We explored the benefits of co-culturing nucleus …

Bilaminar coculture of stem cells and instructive cells for tissue regeneration

AA Allon - 2009 - search.proquest.com
Tissue engineering is a growing and dynamic field with the potential to provide patients with
minimally-invasive treatments that repair or replace dysfunctional musculoskeletal tissues. …

STRUCTURED CO-CULTURE OF STEM CELLS AND DISC CELLS INDUCES MSC DIFFERENTIATION: 4.

AA Allon, K Butcher, RA Schneider… - Spine Journal Meeting …, 2010 - journals.lww.com
00152232-201010001-00004MiscellaneousSpine: Affiliated Society Meeting AbstractsSpine:
Affiliated Society Meeting Abstracts© 2010 Lippincott Williams & Wilkins, Inc. October 2010 …

STRUCTURED CO-CULTURE OF STEM CELLS AND DISC CELLS PREVENT DEGENERATION IN A RAT MODEL: GP56.

AA Allon, N Aurouer, B Yoo, E Liebenberg… - Spine Journal …, 2010 - journals.lww.com
00152232-201010001-00198AbstractSpine: Affiliated Society Meeting AbstractsSpine:
Affiliated Society Meeting Abstracts© 2010 Lippincott Williams & Wilkins, Inc. October 2010 p …

Stem Cells for Disc Repair

AA Allon, Z Buser, S Berven… - Stem Cell And Tissue …, 2011 - books.google.com
The intervertebral disc forms an avascular, fibrocartilaginous joint between adjacent vertebral
bodies and provides flexibility while routinely supporting several multiples of body weight. …