Association of autologous tumor lysate-loaded dendritic cell vaccination with extension of survival among patients with newly diagnosed and recurrent glioblastoma: a …
…, LP Taylor, JK Wu, EM Dunbar, AB Etame… - JAMA …, 2023 - jamanetwork.com
Importance Glioblastoma is the most lethal primary brain cancer. Clinical outcomes for
glioblastoma remain poor, and new treatments are needed. Objective To investigate whether …
glioblastoma remain poor, and new treatments are needed. Objective To investigate whether …
[HTML][HTML] First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma
…, HJ Meisel, J Wu, RP Davis, C Duma, AB Etame… - Journal of translational …, 2018 - Springer
Background Standard therapy for glioblastoma includes surgery, radiotherapy, and
temozolomide. This Phase 3 trial evaluates the addition of an autologous tumor lysate-pulsed …
temozolomide. This Phase 3 trial evaluates the addition of an autologous tumor lysate-pulsed …
[HTML][HTML] Focused ultrasound disruption of the blood-brain barrier: a new frontier for therapeutic delivery in molecular neurooncology
AB Etame, RJ Diaz, CA Smith, TG Mainprize… - Neurosurgical …, 2012 - thejns.org
Recent advances in molecular neurooncology provide unique opportunities for targeted
molecular-based therapies. However, the blood-brain barrier (BBB) remains a major limitation to …
molecular-based therapies. However, the blood-brain barrier (BBB) remains a major limitation to …
Design and potential application of PEGylated gold nanoparticles with size-dependent permeation through brain microvasculature
Gold nanoparticles (AuNPs) have gained prominence in several targeting applications
involving systemic cancers. Their enhanced permeation and retention within permissive tumor …
involving systemic cancers. Their enhanced permeation and retention within permissive tumor …
Enhanced delivery of gold nanoparticles with therapeutic potential into the brain using MRI-guided focused ultrasound
AB Etame, RJ Diaz, MA O'Reilly, CA Smith… - … , Biology and Medicine, 2012 - Elsevier
The blood brain barrier (BBB) is a major impediment to the delivery of therapeutics into the
central nervous system (CNS). Gold nanoparticles (AuNPs) have been successfully …
central nervous system (CNS). Gold nanoparticles (AuNPs) have been successfully …
Outcomes targeting the PD-1/PD-L1 axis in conjunction with stereotactic radiation for patients with non-small cell lung cancer brain metastases
…, LB Harrison, S Sahebjam, JE Gray, AB Etame… - Journal of neuro …, 2017 - Springer
Anti-PD-1/PD-L1 therapies have demonstrated activity in patients with advanced stage non-small
cell lung cancer (NSCLC). However, little is known about the safety and feasibility of …
cell lung cancer (NSCLC). However, little is known about the safety and feasibility of …
Impact of anesthesia on transcranial electric motor evoked potential monitoring during spine surgery: a review of the literature
Object Transcranial motor evoked potential (TcMEP) monitoring is frequently used in complex
spinal surgeries to prevent neurological injury. Anesthesia, however, can significantly …
spinal surgeries to prevent neurological injury. Anesthesia, however, can significantly …
Hypofractionated stereotactic re-irradiation with pembrolizumab and bevacizumab in patients with recurrent high-grade gliomas: results from a phase I study
…, ND Tran, JA Arrington, R Macaulay, AB Etame… - Neuro …, 2021 - academic.oup.com
Background Radiotherapy may synergize with programmed cell death 1 (PD1)/PD1 ligand (PD-L1)
blockade. The purpose of this study was to determine the recommended phase II …
blockade. The purpose of this study was to determine the recommended phase II …
Surgical management of symptomatic cervical or cervicothoracic kyphosis due to ankylosing spondylitis
Study Design. Literature review. Objective. To evaluate surgical management and outcomes
in the treatment of severe chin-on-chest deformities due to ankylosing spondylitis (AS). …
in the treatment of severe chin-on-chest deformities due to ankylosing spondylitis (AS). …
[HTML][HTML] Outcomes after surgery for cervical spine deformity: review of the literature
Object Symptomatic cervical kyphosis can result from a variety of causes. Symptoms can
include pain, neurological deficits, and functional limitation due to loss of horizontal gaze. …
include pain, neurological deficits, and functional limitation due to loss of horizontal gaze. …