The chondrogenic potential of human bone-marrow-derived mesenchymal progenitor cells
…, L Solchaga, AI Caplan, VM Goldberg, B Johnstone - JBJS, 1998 - journals.lww.com
Mesenchymal progenitor cells provide a source of cells for the repair of musculoskeletal
tissue. However, in vitro models are needed to study the mechanisms of differentiation of …
tissue. However, in vitro models are needed to study the mechanisms of differentiation of …
BMP‐2 induction and TGF‐β1 modulation of rat periosteal cell chondrogenesis
…, VM Goldberg, JU Yoo, B Johnstone - Journal of cellular …, 2001 - Wiley Online Library
Periosteum contains osteochondral progenitor cells that can differentiate into osteoblasts and
chondrocytes during normal bone growth and fracture healing. TGF‐β1 and BMP‐2 have …
chondrocytes during normal bone growth and fracture healing. TGF‐β1 and BMP‐2 have …
Secretion of angiogenic and antiapoptotic factors by human adipose stromal cells
…, JE Bovenkerk, CL Pell, BH Johnstone… - Circulation, 2004 - Am Heart Assoc
Background— The delivery of autologous cells to increase angiogenesis is emerging as a
treatment option for patients with cardiovascular disease but may be limited by the …
treatment option for patients with cardiovascular disease but may be limited by the …
In vitrochondrogenesis of bone marrow-derived mesenchymal progenitor cells
B Johnstone, TM Hering, AI Caplan… - Experimental cell …, 1998 - Elsevier
A culture system that facilitates the chondrogenic differentiation of rabbit bone marrow-derived
mesenchymal progenitor cells has been developed. Cells obtained in bone marrow …
mesenchymal progenitor cells has been developed. Cells obtained in bone marrow …
A population of multipotent CD34-positive adipose stromal cells share pericyte and mesenchymal surface markers, reside in a periendothelial location, and stabilize …
…, W Arap, R Pasqualini, BH Johnstone… - Circulation …, 2008 - Am Heart Assoc
It has been shown that stromal–vascular fraction isolated from adipose tissues contains an
abundance of CD34 + cells. Histological analysis of adipose tissue revealed that CD34 + …
abundance of CD34 + cells. Histological analysis of adipose tissue revealed that CD34 + …
[HTML][HTML] IL-1Ra gene transfer potentiates BMP2-mediated bone healing by redirecting osteogenesis toward endochondral ossification
…, CL De Padilla, RF Coghlan, B Johnstone… - Molecular Therapy, 2023 - cell.com
An estimated 100,000 patients each year in the United States suffer severe disability from
bone defects that fail to heal, a condition where bone-regenerative therapies could provide …
bone defects that fail to heal, a condition where bone-regenerative therapies could provide …
Radiolabeled cell distribution after intramyocardial, intracoronary, and interstitial retrograde coronary venous delivery: implications for current clinical trials
…, P Rogers, ET Price, AC Yeung, BH Johnstone… - Circulation, 2005 - Am Heart Assoc
Background— Several clinical studies are evaluating the therapeutic potential of delivery of
various progenitor cells for treatment of injured hearts. However, the actual fate of delivered …
various progenitor cells for treatment of injured hearts. However, the actual fate of delivered …
A quadripotential mesenchymal progenitor cell isolated from the marrow of an adult mouse
…, A Awadallah, JU Yoo, B Johnstone… - Journal of Bone and …, 1999 - academic.oup.com
Adult marrow contains mesenchymal progenitor cells (MPCs) that have multiple differentiation
potentials. A conditionally immortalized MPC clone, BMC9, has been identified that …
potentials. A conditionally immortalized MPC clone, BMC9, has been identified that …
Cyclic hydrostatic pressure enhances the chondrogenic phenotype of human mesenchymal progenitor cells differentiated in vitro
…, KJ Jepsen, M Nerlich, B Johnstone - Journal of …, 2003 - Wiley Online Library
Much attention has been given to the influences of bioactive factors on mesenchymal
progenitor cell differentiation and proliferation, but few studies have examined the effect of …
progenitor cell differentiation and proliferation, but few studies have examined the effect of …
[PDF][PDF] Tissue engineering for articular cartilage repair—the state of the art
B Johnstone, M Alini, M Cucchiarini, GR Dodge… - Eur Cell Mater, 2013 - Citeseer
Adult articular cartilage exhibits little capacity for intrinsic repair, and thus even minor injuries
or lesions may lead to progressive damage and osteoarthritic joint degeneration, resulting …
or lesions may lead to progressive damage and osteoarthritic joint degeneration, resulting …