Approximately 10% of dementia patients have idiopathic normal pressure hydrocephalus (iNPH),
an expansion of the cerebrospinal fluid (CSF)-filled brain ventricles. iNPH and …

Hydrocephalus, characterized by cerebral ventricular dilatation, is routinely attributed to
primary defects in cerebrospinal fluid (CSF) homeostasis. This fosters CSF shunting as the …

Hydrocephalus is the most common neurosurgical disorder worldwide and is characterized
by enlargement of the cerebrospinal fluid (CSF)-filled brain ventricles resulting from failed …

Congenital hydrocephalus (CH), characterized by enlarged brain ventricles, is considered a
disease of excessive cerebrospinal fluid (CSF) accumulation and thereby treated with …

The choroid plexus (ChP) is the blood-cerebrospinal fluid (CSF) barrier and the primary
source of CSF. Acquired hydrocephalus, caused by brain infection or hemorrhage, lacks drug …

Importance Moyamoya disease (MMD), a progressive vasculopathy leading to narrowing and
ultimate occlusion of the intracranial internal carotid arteries, is a cause of childhood stroke…

Recent data have implicated inflammation of the cerebrospinal fluid spaces after
subarachnoid, intraventricular, and intracerebral hemorrhage to be a critical driver of multiple …

To elucidate the pathogenesis of vein of Galen malformations (VOGMs), the most common
and most severe of congenital brain arteriovenous malformations, we performed an …

The lack of effective treatments for autism spectrum disorder (ASD) and congenital
hydrocephalus (CH) reflects the limited understanding of the biology underlying these common …

Fibrosis is a macrophage-driven process of uncontrolled extracellular matrix accumulation.
Neuronal guidance proteins such as netrin-1 promote inflammatory scarring. We found that …