The evaluation and management of adult patients with spinal deformity has undergone a
rapid evolution in the past decade. Increasing knowledge about the natural history of adult …

Each year in the United States, 6.2 million fractures occur. Of these, 5% to 10% exhibit
delayed healing or nonunion. Autogenous bone graft from the iliac crest or local sources has …

Spinal infections can occur in a variety of clinical situations. Their presentation ranges from
the infant with diskitis who is unwilling to crawl or walk to the adult who develops an infection …

Study Design. An in vitro biomechanical study of C4–C5 intervertebral disc replacement
using a cadaveric model. Objectives. To investigate the degree of motion afforded by a ball-and-…

Study design Cross-sectional cohort analysis of patients with Modic Changes (MC). Objective
Our goal was to characterize the molecular and cellular features of MC bone marrow and …

Study Design. The efficacy of a specially designed mineralized bovine collagen matrix as a
carrier for bone marrow stem cells was studied in a rabbit posterolateral spinal fusion model. …

Bone graft substitutes may be broadly classified as mineralized and demineralized
preparations. This article reviews the basic science and biology underlying each preparation. A …

INTERVERTEBRAL DISC/BONE MARROW CROSS-TALK WITH MODIC CHANGE... : Spine
Journal Meeting Abstracts INTERVERTEBRAL DISC/BONE MARROW CROSS-TALK WITH …

Background: Cervical total disk replacement (TDR) is intended to address pain and preserve
motion between vertebral bodies in patients with symptomatic cervical disk disease. Two-…

Study Design. Retrospective review of prospectively collected data. Objective. The aim of
this study was to examine which radiographic parameters and surgical strategies are most …