Tumor inhibitors. XLVII. Vernodalin and vernomygdin, two new cytotoxic sesquiterpene lactones from Vernonia amygdalina Del

…, RJ Hemingway, A Karim, D Werner - The Journal of organic …, 1969 - ACS Publications
A chloroform extract of Vernonia amygdalina Del. was found to show significant inhibitory
activity in vitro against cells derived from human carcinoma of the nasopharynx (KB) carried in …

Tumor inhibitors. XXXI. Vernolepin, a novel elemanolide dilactone tumor inhibitor from Vernonia hymenolepis

SM Kupchan, RJ Hemingway, D Werner… - Journal of the …, 1968 - ACS Publications
(3) Leaves were collected in Ethiopia in Jan 1965. The authors acknowledge with thanks
the receipt of the dried plant material from Dr. Robert E. Perdue, Jr., US Department of …

Human RNPS1 and its associated factors: a versatile alternative pre-mRNA splicing regulator in vivo

E Sakashita, S Tatsumi, D Werner, H Endo… - … and cellular biology, 2004 - Taylor & Francis
Human RNPS1 was originally purified and characterized as a pre-mRNA splicing activator,
and its role in the postsplicing process has also been proposed recently. To search for …

Folding of the four domains and dimerization are impaired by the Gly446. fwdarw. Glu exchange in human glutathione reductase. Implications for the design of …

A Nordhoff, US Buecheler, D Werner, RH Schirmer - Biochemistry, 1993 - ACS Publications
Revised Manuscript Received February 4, 1993 abstract: Glutathione reductase (NADPH+
GSSG+ H+-*• NADP++ 2GSH) is a homodimeric flavoenzyme of known geometry. Each …

A human nuclear protein with sequence homology to a family of early S phase proteins is required for entry into S phase and for cell division

…, SE Kearsey, W Ansorge, D Werner - Journal of cell …, 1994 - journals.biologists.com
Molecular cloning and characterisation of a human nuclear protein designated BM28 is
reported. On the amino acid level this 892 amino acid protein, migrating on SDS-gels as a 125 …

Tumor inhibitors. XLVI. Vernolepin, a novel sesquiterpene dilactone tumor inhibitor from Vernonia hymenolepis

SM Kupchan, RJ Hemingway, D Werner… - The Journal of Organic …, 1969 - ACS Publications
An alcoholic extract of Vernonia hymenolepis A. Rich, was found to show significant
inhibitory activity in vitro against cells derived from human carcinoma of the nasopharynx (KB) …

DNA end-independent activation of DNA-PK mediated via association with the DNA-binding protein C1D

U Yavuzer, GCM Smith, T Bliss, D Werner… - Genes & …, 1998 - genesdev.cshlp.org
DNA-dependent protein kinase (DNA-PK), which is involved in DNA double-strand break
repair and V(D)J recombination, is comprised of a DNA-targeting component termed Ku and an …

Nubac disc arthroplasty: preclinical studies and preliminary safety and efficacy evaluations

QB Bao, M Songer, L Pimenta, D Werner… - SAS journal, 2007 - Elsevier
BACKGROUND: Disc arthroplasty is gaining popularity for treatment of low-back pain caused
by degenerative disc disease (DDD). It can involve total disc replacement or partial disc or …

Randomized trial on routine vs. provisional T-stenting in the treatment of de novo coronary bifurcation lesions

…, RP Kienzle, HP Bestehorn, KD Werner… - European heart …, 2008 - academic.oup.com
Aims We investigated whether routine T-stenting reduces restenosis of the side branch as
compared with provisional T-stenting in patients with de novo coronary bifurcation lesions. …

Cloning and sequencing of mammalian glutathione reductase cDNA

…, X Lu, RH Schirmer, D Werner - European journal of …, 1990 - Wiley Online Library
The molecular cloning of a partial cDNA to mouse glutathione reductase mRNA and of a full‐length
cDNA to the mRNA of the human enzyme is described. An initial cDNA clone …