Evaluation of Diffuse Myocardial Fibrosis in Heart Failure With Cardiac Magnetic Resonance Contrast-Enhanced T1 Mapping
…, J Cherayath, P Aksit, SN Gupta, DM Kaye… - Journal of the American …, 2008 - jacc.org
Objectives : The purpose of this study was to investigate a noninvasive method for quantifying
diffuse myocardial fibrosis with cardiac magnetic resonance imaging (CMRI). Background …
diffuse myocardial fibrosis with cardiac magnetic resonance imaging (CMRI). Background …
High-fiber diet and acetate supplementation change the gut microbiota and prevent the development of hypertension and heart failure in hypertensive mice
…, NW Rajapakse, A El-Osta, CR Mackay, DM Kaye - Circulation, 2017 - Am Heart Assoc
Background: Dietary intake of fruit and vegetables is associated with lower incidence of
hypertension, but the mechanisms involved have not been elucidated. Here, we evaluated the …
hypertension, but the mechanisms involved have not been elucidated. Here, we evaluated the …
Effect of sunlight and season on serotonin turnover in the brain
Alterations in monoaminergic neurotransmission in the brain are thought to underlie
seasonal variations in mood, behaviour, and affective disorders. We took blood samples from …
seasonal variations in mood, behaviour, and affective disorders. We took blood samples from …
[HTML][HTML] Adverse consequences of high sympathetic nervous activity in the failing human heart
DM Kaye, J Lefkovits, GL Jennings, P Bergin… - Journal of the American …, 1995 - Elsevier
OBJECTIVES.: In view of previous experimental evidence relating sympathetic nervous
overactivity in the heart to myocardial necrosis and ventricular arrhythmias, we prospectively …
overactivity in the heart to myocardial necrosis and ventricular arrhythmias, we prospectively …
Sympathetic augmentation in hypertension: role of nerve firing, norepinephrine reuptake, and angiotensin neuromodulation
MP Schlaich, E Lambert, DM Kaye, Z Krozowski… - …, 2004 - Am Heart Assoc
There is growing evidence that essential hypertension is commonly neurogenic and is initiated
and sustained by sympathetic nervous system overactivity. Potential mechanisms include …
and sustained by sympathetic nervous system overactivity. Potential mechanisms include …
Controlled trial of continuous positive airway pressure in obstructive sleep apnea and heart failure
DR Mansfield, NC Gollogly, DM Kaye… - American journal of …, 2004 - atsjournals.org
Obstructive sleep apnea (OSA) is highly prevalent among patients with congestive heart
failure (CHF) and may contribute to progression of cardiac dysfunction via hypoxia, elevated …
failure (CHF) and may contribute to progression of cardiac dysfunction via hypoxia, elevated …
Air versus oxygen in ST-segment–elevation myocardial infarction
…, B Barger, AH Ellims, AJ Taylor, IT Meredith, DM Kaye - Circulation, 2015 - Am Heart Assoc
Background— Oxygen is commonly administered to patients with ST-elevation–myocardial
infarction despite previous studies suggesting a possible increase in myocardial injury as a …
infarction despite previous studies suggesting a possible increase in myocardial injury as a …
Relation between cardiac sympathetic activity and hypertensive left ventricular hypertrophy
MP Schlaich, DM Kaye, E Lambert, M Sommerville… - Circulation, 2003 - Am Heart Assoc
Background— Left ventricular (LV) hypertrophy is an independent risk factor for cardiovascular
morbidity and mortality in hypertensive subjects. Sympathetic activation has been …
morbidity and mortality in hypertensive subjects. Sympathetic activation has been …
Cardiac sympathetic nerve function in congestive heart failure
…, B Rundqvist, AA Quyyumi, G Lambert, DM Kaye… - Circulation, 1996 - Am Heart Assoc
Background Increased availability of norepinephrine (NE) for activation of cardiac
adrenoceptors (increased cardiac adrenergic drive) and depletion of myocardial NE stores may …
adrenoceptors (increased cardiac adrenergic drive) and depletion of myocardial NE stores may …
Refractory cardiac arrest treated with mechanical CPR, hypothermia, ECMO and early reperfusion (the CHEER trial)
Introduction Many patients who suffer cardiac arrest do not respond to standard
cardiopulmonary resuscitation. There is growing interest in utilizing veno-arterial extracorporeal …
cardiopulmonary resuscitation. There is growing interest in utilizing veno-arterial extracorporeal …