The concept of “aging” is defined as the set of gradual and progressive changes in an organism
that leads to an increased risk of weakness, disease, and death. This process may occur …

The episodic secretion of growth hormone(GH) depends on the rhythmic alternation in the
hypothalamic release of GHRH and somatostatin(SS) into the hypophyseal portal system. In …

Several ultraviolet (UV) filters exhibit estrogenic, some also anti‐androgenic activity. They
are present in waste water treatment plants, surface waters and biosphere including human …

Objective: The purpose of this study was to determine whether rhGH administered locally
during the surgical placement of an implant, in the tibia of an osteoporotic rabbit model, would …

Aging is associated with an increase in oxidative stress and inflammation. The aim of this
study was to investigate the effect of aging on various physiological parameters related to …

Introduction: Previous studies have shown that melatonin, an anti-oxidant molecule secreted
from the pineal gland, is a positive regulator of bone mass. However, the potential effects of …

Purpose: The aim of this study was to assess the effect of local melatonin administration on
bone osseointegration around implants in rabbit tibiae. Material and Methods: Ten female, 6‐…

Low mitochondriogenesis is critical to explain loss of muscle function in aging and in the
development of frailty. The aim of this work was to explain the mechanism by which …

Aging is a physiological state in which a progressive decline in organ functions is accompanied
by the development of age-related diseases. Resveratrol supplementation has been …

The aim of the present study was to investigate the effect of aging on several parameters
related to glucose homeostasis and insulin resistance in pancreas and how melatonin …