Successful treatment of thoracolumbar fractures with short-segment pedicle instrumentation

D Gelb, S Ludwig, JE Karp, EH Chung… - Clinical Spine …, 2010 - journals.lww.com
… Reprints: Daniel Gelb, MD, Department of Orthopaedics, University of Maryland Medical
Center, 22 South Greene Street, Suite S11B, Baltimore, MD 21201 (e-mail: [email protected]) …

Athletic cervical spine injury in the setting of fusion failure of the anterior and posterior atlas

BM Petre, JE Karp, LH Riley III - Orthopedics, 2012 - journals.healio.com
This article describes a rare congenital abnormality of anterior and posterior C1 fusion
failure presenting after an acute athletic injury to the fibrous nonunion. C1 congenital …

The role of minimally invasive surgery in thoracolumbar spine trauma

JE Karp, SC Ludwig - Seminars in Spine Surgery, 2011 - Elsevier
Minimally invasive surgical stabilization of thoracolumbar spine injuries has the potential to
reduce surgical morbidity, improve postoperative care and rehabilitation, and even serve as …

A novel radiographic targeting guide for percutaneous placement of transfacet screws in the cervical spine with limited fluoroscopy: A cadaveric feasibility study

DM Jackson, JE Karp, JR O'Brien… - International Journal of …, 2012 - ijssurgery.com
Background We describe a technique for percutaneous transfacet screw placement in the
cervical spine without the need for lateral-view fluoroscopy. Methods Previously established …

Trauma MIS

JE Karp, SC Ludwig - Techniques in Orthopaedics, 2011 - journals.lww.com
Minimally invasive surgical stabilization of thoracolumbar spinal injuries has the potential to
reduce surgical morbidity and improve the postoperative care and rehabilitation of trauma …

Clinical and biologic activity of the farnesyltransferase inhibitor R115777 in adults with refractory and relapsed acute leukemias: a phase 1 clinical-laboratory …

JE Karp, JE Lancet, SH Kaufmann… - Blood, The Journal …, 2001 - ashpublications.org
R115777 is a nonpeptidomimetic enzyme-specific inhibitor of farnesyl protein transferase (FT)
that was developed as a potential inhibitor of Ras protein signaling, with antitumor activity …

Targeting Vascular Endothelial Growth Factor for Relapsed and Refractory Adult Acute Myelogenous Leukemias: Therapy with Sequential 1-β-d …

JE Karp, I Gojo, R Pili, CD Gocke, J Greer, C Guo… - Clinical Cancer …, 2004 - AACR
Purpose: Vascular endothelial growth factor (VEGF) promotes acute myelogenous leukemia
(AML) cell growth and survival and may contribute to drug resistance. bevacizumab, an anti-…

Phase I and pharmacologic trial of cytosine arabinoside with the selective checkpoint 1 inhibitor Sch 900776 in refractory acute leukemias

JE Karp, BM Thomas, JM Greer, C Sorge, SD Gore… - Clinical Cancer …, 2012 - AACR
Purpose: Incorporation of cytarabine into DNA activates checkpoint kinase 1 (Chk1), which
stabilizes stalled replication forks, induces S-phase slowing, and diminishes cytarabine …

A Phase I study of the novel ribonucleotide reductase inhibitor 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP, Triapine®) in combination with the …

JE Karp, FJ Giles, I Gojo, L Morris, J Greer, B Johnson… - Leukemia research, 2008 - Elsevier
Triapine ® is a potent ribonucleotide reductase (RR) inhibitor that depletes intracellular
deoxyribonculeotide pools, especially dATP. We designed a Phase I trial of Triapine followed by …

[CITATION][C] NEEL ANAND, MD, Cedars-Sinai Spine Center, Cedars-Sinai Medical Center, Los Angeles, California JAHANGIR ASGHAR, MD, Shriners Hospitals for …

…, R HÄRTL, J HAW, C IDLER, AR JAMES, JE KARP