Numerous experimental studies in recent years have suggested that erythropoietin (EPO) is
an endogenous mediator of neuroprotection in various central nervous system disorders, …

The treatment of patients with refractory epilepsy has always been challenging. Despite the
availability of multiple antiepileptic medications and surgical procedures with which to resect …

Traumatic brain injuries (TBIs) are associated with high morbidity and mortality due to both
the original insult as well as the destructive biological response that follows. Medical …

Pyroglutamate helix B surface peptide (pHBSP) is an 11 amino acid peptide, designed to
interact with a novel cell surface receptor, composed of the classical erythropoietin (EPO) …

The purpose of this study was to investigate the increased susceptibility of the brain, after a
controlled mild cortical impact injury, to a secondary ischemic insult. The effects of the …

Background The placement of iliac screws is a biomechanically sound method for the
stabilization of long multi-segment lumbar constructs. Traditional techniques for the placement of …

OBJECTIVE To determine the rate of successful nonoperative management and risk factors
for instability in patients with acute traumatic, unilateral, nondisplaced cervical facet fractures…

The current standard of practice is to maintain normothermia in traumatic brain injury (TBI)
patients despite the theoretical benefits of hypothermia and numerous animal studies with …

Background: The physiological and neurochemical changes that accompany brain death are
not well described. Materials and Methods: A retrospective observational study of patients …

Patient monitoring during the administration of anesthesia is essential for safety and a core
tenet of anesthesiology. The American Society of Anesthesiology established guidelines and …