Background Context Various surface modifications, often incorporating roughened or porous
surfaces, have recently been introduced to enhance osseointegration of interbody fusion …

Osteopetrosis is a group of rare sclerosing bone dysplasias. Orthopedic concerns in Osteopetrosis
are principally related to the characteristic brittle "marble bone" in which fractures may …

Study Design. A retrospective study to determine the efficacy of posterior-only unit rod
instrumentation and fusion in a skeletally immature neuromuscular scoliosis population. Objective. …

Background A retrospective clinical case series study was conducted to evaluate the use of
a novel, spherical bioactive glass bone graft (BioSphere Putty) as a graft material for cervical …

The ability of particulate bioactive glass to function as an effective bone graft material is
directly related to its in vivo dissolution, ion release, and interparticle spacing (area associated …

Background Anterior cervical discectomy and fusion (ACDF) at 3 or more levels remains
challenging, with reported high pseudarthrosis rates and implant-related complications. Porous …

Study Design. A case report of a patient with autosomal dominant osteopetrosis and
neuromuscular scoliosis who required surgical instrumentation and fusion of her spine. Objective. …

Background Bioactive glasses have unique bone forming properties that have been used
as a bone graft substitute for anterior cervical discectomy and fusions (ACDFs). Bone graft …

Chronic disc degeneration with osteophyte formation causing nerve root or spinal cord
compression is the most common indication for cervical spine surgery. These findings are …

Study Design. Forty patients were enrolled in 2 FDA-approved pilot Investigational Device
Exemption (IDE) studies using Cortoss for the treatment of vertebral compression fractures (…