User profiles for Mark E. Shaffrey

Mark E Shaffrey

Professor of Neurosurgery, University of Virginia
Verified email at virginia.edu
Cited by 8622

Decompressive bifrontal craniectomy in the treatment of severe refractory posttraumatic cerebral edema

RS Polin, ME Shaffrey, CA Bogaev, N Tisdale… - …, 1997 - journals.lww.com
OBJECTIVE: The management of malignant posttraumatic cerebral edema remains a frustrating
endeavor for the neurosurgeon and the intensivist. Mortality and morbidity rates remain …

Imaging Tumor Angiogenesis With Contrast Ultrasound and Microbubbles Targeted to αvβ3

…, JE Carpenter, AL Klibanov, S Kaul, ME Shaffrey… - Circulation, 2003 - Am Heart Assoc
Background— Angiogenesis is a critical determinant of tumor growth and metastasis. We
hypothesized that contrast-enhanced ultrasound (CEU) with microbubbles targeted to α v -…

Surgical approaches for the correction of unstable thoracolumbar burst fractures: a retrospective analysis of treatment outcomes

OA Danisa, CI Shaffrey, JA Jane, R Whitehill… - Journal of …, 1995 - thejns.org
✓ The authors retrospectively studied 49 nonparaplegic patients who sustained acute
unstable thoracolumbar burst fractures. All patients underwent surgical treatment and were …

Neurosurgical applications of fibrin glue: augmentation of dural closure in 134 patients

CI Shaffrey, WD Spotnitz, ME Shaffrey, JA Jane - Neurosurgery, 1990 - journals.lww.com
: In a wide variety of neurosurgical procedures performed on 134 patients over a 3-year period.
fibrin glue has been applied as an adjunct to dural closure. Overall success at preventing …

Safety and efficacy of a novel polyethylene glycol hydrogel sealant for watertight dural repair

…, RF Spetzler, T Payner, G Rosseau, ME Shaffrey… - Journal of …, 2007 - thejns.org
Object The authors prospectively evaluated the safety and efficacy of a novel polyethylene
glycol (PEG) hydrogel sealant in patients undergoing elective cranial surgery with …

Part I: Spinal-cord neoplasms—intradural neoplasms

DE Traul, ME Shaffrey, D Schiff - The lancet oncology, 2007 - thelancet.com
Intradural spinal-cord tumours are an uncommon but important consideration in the differential
diagnosis of patients with back pain, radicular pain, sensorimotor deficits, or sphincter …

Detection of soluble E-selectin, ICAM-1, VCAM-1, and L-selectin in the cerebrospinal fluid of patients after subarachnoid hemorrhage

RS Polin, M Bavbek, ME Shaffrey, K Billups… - Journal of …, 1998 - thejns.org
Object. The goal of this study was to explore whether the levels of soluble adhesion molecules
were elevated in cerebrospinal fluid (CSF) after subarachnoid hemorrhage (SAH). This …

Gamma Knife radiosurgery to the surgical cavity following resection of brain metastases

…, RJ Oskouian, N Pouratian, ME Shaffrey… - Journal of …, 2009 - thejns.org
Object This study evaluated the efficacy of postoperative Gamma Knife surgery (GKS) to the
tumor cavity following gross-total resection of a brain metastasis. Methods A retrospective …

Defining the minimum clinically important difference for grade I degenerative lumbar spondylolisthesis: insights from the Quality Outcomes Database

…, JR Slotkin, EA Potts, ME Shaffrey, CI Shaffrey… - Neurosurgical …, 2018 - thejns.org
OBJECTIVE Patient-reported outcomes (PROs) play a pivotal role in defining the value of
surgical interventions for spinal disease. The concept of minimum clinically important …

Advances in brain tumor surgery

…, N Pouratian, J Sherman, G Ahmed, ME Shaffrey - Neurologic clinics, 2007 - Elsevier
Advances in the fields of molecular and translational research, oncology, and surgery have
emboldened the medical community to believe that intrinsic brain tumors may be treatable. …