Bone has well documented natural healing capacity that normally is sufficient to repair fractures
and other common injuries. However, the properties of bone change throughout life, and …

Background: Adhesive capsulitis of the shoulder involves loss of passive range of motion
with associated pain and can develop spontaneously, with no obvious injury or inciting event. …

Background: End-stage knee osteoarthritis (OA) is a highly debilitating disease for which
total knee arthroplasty (TKA) serves as an effective treatment option. Although a genetic …

Background: Cannabidiol (CBD) is a cannabis derivative that has been popularized as a
medicinal product with analgesic and anti-inflammatory effects. Given the anecdotal …

This review surveys the use of pluripotent and multipotent stem cells in skeletal tissue engineering.
Specific emphasis is focused on evaluating the function and activities of these cells in …

Background Although a genetic component to hip osteoarthritis (OA) has been described,
focused evaluation of the genetic components of end-stage disease is limited. We present a …

Musculoskeletal disorders constitute a substantial disease burden. Neither conservative
management nor surgical intervention provides adequate treatment for several pathologies. As …

The utility of restriction endonucleases as a tool in molecular biology is in large part due to
the high degree of specificity with which they cleave well-characterized DNA recognition …

Background Mice with a loss of function mutation in Wdpcp were described previously to
display severe birth defects in the developing heart, neural tube, and limb buds. Further …

Background: Recently, the posterior horn lateral meniscal oblique radial tear (LMORT) was
identified in 12% of acute anterior cruciate ligament (ACL) injuries. However, patient-…