Background: Cervical spondylotic myelopathy is the leading cause of spinal cord
dysfunction worldwide. The objective of this study was to evaluate the impact of surgical …

Purpose: To prospectively evaluate whether quantitative and qualitative magnetic resonance
(MR) imaging assessments after spinal cord injury (SCI) correlate with patient neurologic …

Study Design: Guideline development. Objectives: The objective of this study is to develop
guidelines that outline how to best manage (1) patients with mild, moderate, and severe …

Minocycline, a clinically used tetracycline for over 40 years, crosses the blood–brain barrier
and prevents caspase up‐regulation. It reduces apoptosis in mouse models of Huntington's …

Object Rates of complications associated with the surgical treatment of cervical spondylotic
myelopathy (CSM) are not clear. Appreciating these risks is important for patient counseling …

Spine surgery has experienced much technological innovation over the past several decades.
The field has seen advancements in operative techniques, implants and biologics, and …

Following a controlled, severe contusion lesion to the lower thoracic spinal cord in adult rats,
we found that apoptosis occurred in cells located in both gray and white matter. This …

Background: The reproducibility and repeatability of modern systems for classification of
thoracolumbar injuries have not been sufficiently studied. We assessed the interobserver and …

BACKGROUND: Spine surgery is complicated by an incidence of 1% to 9% of surgical site
infection (SSI). The most common organisms are gram-positive bacteria and are endogenous…

Objective: To develop recommendations on the timing of surgical decompression in patients
with traumatic spinal cord injury (SCI) and central cord syndrome. Methods: A systematic …