Many approaches are used to repair skeletal defects in reconstructive orthopaedic surgery,
and bone grafting is involved in virtually every procedure. The type of bone graft used …

The ability of bone to repair and regenerate after injury and to remodel in response to physical
stress is remarkable. Osteoblastic bone formation and osteoclastic bone resorption dictate …

Optimal bone graft substances generally possess one or more of three essential elements:(1)
osteoinductive factors that induce the various stages of bone regeneration,(2) …

Study Design. A retrospective chart review was conducted for 112 patients who underwent
revision posterior lumbar spine decompression, fusion, and segmental instrumentation. …

Piriformis syndrome (PS) remains a controversial and nebulous diagnosis for back and
buttock pain. This can be ascribed secondarily to an unclear consensus on the definition and …

Fibrous dysplasia is proliferation of fibrous tissue within the bone marrow causing osteolytic
lesions and pathologic fractures. Recently, second generation bisphosphonates have …

Study Design. Retrospective, economic analysis. Objective. To study patient profile associated
with preoperative chronic opioid therapy (COT), and study COT as a risk factor for 90-day …

Background and purpose — Outcome measurement has been shown to improve performance
in several fields of healthcare. This understanding has driven a growing interest in value-…

Preclinical proof-of-concept, feasibility and efficacy studies in lower animals resulted in the
accumulation of data that served as a backbone for clinical trials with the recombinant, …

Background: Preoperative opioid use results in adverse outcomes and higher costs after
elective surgery. However, duration thresholds for higher risk are not entirely known. Therefore, …