Background Emerging evidence has suggested that circulating microRNAs (miRNAs) in
body fluids have novel diagnostic and prognostic significance for patients with malignant …

Osteosarcoma is a rare disease diagnosed as malignant bone tumor. It is generally refractory
to chemotherapy, which contributes to its poor prognosis. The reversal of chemoresistance …

Bone and soft-tissue sarcomas are rare malignancies with histological diversity and tumor
heterogeneity, leading to the lack of a common molecular target. Telomerase is a key enzyme …

Background Osteosarcoma (OS) is a malignant bone tumor primarily affecting children and
adolescents. The prognosis of chemotherapy-refractory OS patients is poor. We developed a …

Soft tissue sarcoma (STS) is a rare cancer that develops from soft tissues in any part of the
body. Despite major advances in the treatment of STS, patients are often refractory to …

Osteosarcoma is an aggressive malignant bone tumor that causes bone destruction. Although
tumor‐specific replicating oncolytic adenovirus OBP ‐301 induces an antitumor effect in …

Background Posterior fossa decompression (PFD) has been widely accepted for the surgical
treatment for Chiari malformation type I (CM1). However, inadequate decompression …

Soft-tissue sarcoma (STS) is a heterogeneous group of rare tumors originating predominantly
from the embryonic mesoderm. Despite the development of combined modalities including …

Discussion Extraskeletal myxoid chondrosarcoma is a rare tumor that accounts for approximately
3% of all soft tissue sarcomas [1]. It occurs more frequently in men than in women (at a …

Osteosarcoma is the most common malignant primary bone tumor. Despite advances in
multi-agent chemotherapy, poor response to chemotherapy is one of the critical prognostic …