Three-dimension (3D)-printed bioscaffolds are precise and personalized for bone regeneration.
However, customized 3D scaffolds may activate the immune response in vivo and …

The stiffness of the extracellular matrix (ECM) plays an important role in regulating the
cellular programming. However, the mechanical characteristics of ECM affecting cell …

Along with the massive use of implants in orthopaedic surgeries in recent few decades,
there has been a tremendous demand for the surface modification of the implants to avoid …

Osteoarthritis (OA), characterized by cartilage erosion, synovium inflammation, and subchondral
bone remodeling, is a common joint degenerative disease worldwide. OA pathogenesis …

Osteoarthritis (OA) is a common articular degenerative disease characterized by loss of
cartilage matrix and subchondral bone sclerosis. Kartogenin (KGN) has been reported to …

In two-dimensional (2D) systems, high mobility is typically achieved in low-carrier-density
semiconductors and semimetals. Here, we discover that the nanobelts of Weyl semimetal …

Recent evidence indicates that the mitochondrial functions of chondrocytes are impaired in
the pathogenesis of osteoarthritis (OA). Melatonin can attenuate cartilage degradation …

Annulus fibrosus (AF) tissue engineering has attracted increasing attention as a promising
therapy for degenerative disc disease (DDD). However, regeneration of AF still faces many …

BACKGROUND: Osteoporotic compression fractures (OVCFs) commonly occur in aged
people, and as much as one-third of these fractures progress to chronic pain. Kyphoplasty (KP) …

Objectives Dementia is a common mental disorder that affects the life quality in elders.
Recently, emerging studies reported the negative impacts of dementia on prognosis after hip …