Research of Pesticide Metabolites in Human Brain Tumor Tissues by Chemometrics-Based Gas Chromatography–Mass Spectrometry Analysis for a Hypothetical …

K Louati, F Kolsi, R Kallel, Y Gdoura, M Borni… - ACS …, 2023 - ACS Publications
Pesticides are widely used, resulting in continuing human exposure with potential health
impacts. Some exposures related to agricultural works have been associated with neurological …

Differential Proteome Profiling Analysis under Pesticide Stress by the Use of a Nano-UHPLC-MS/MS Untargeted Proteomic-Based Approach on a 3D-Developed …

…, A Maalej, F Kolsi, R Kallel, Y Gdoura… - Journal of Proteome …, 2023 - ACS Publications
High-grade gliomas represent the most common group of infiltrative primary brain tumors in
adults associated with high invasiveness, agressivity, and resistance to therapy, which …

Shotgun Proteomic-Based Approach with a Q-Exactive Hybrid Quadrupole-Orbitrap High-Resolution Mass Spectrometer for Protein Adductomics on a 3D Human …

…, A Maalej, F Kolsi, R Kallel, Y Gdoura… - Journal of Proteome …, 2023 - ACS Publications
Pesticides are increasingly used in combinations in crop protection, resulting in enhanced
toxicities for various organisms. Although protein adductomics is challenging, it remains a …

Intraventricular glioblastomas

AB Nsir, Y Gdoura, QA Thai, AZ Kassar, N Hattab… - World neurosurgery, 2016 - Elsevier
Background and Importance Although glioblastoma is the most common primary brain tumor,
primary intraventricular locations are extremely rare; only 21 cases have been reported to …

Facet arthrodesis with the FFX device: one-year results from a prospective multicenter study

R Srour, Y Gdoura, M Delaitre, J Mortada… - International Journal of …, 2020 - ijssurgery.com
Background: Facet osteosynthesis can be performed to treat facet syndrome (FS) and reduce
spinal instability following laminectomy in patients with lumbar spinal stenosis (LSS). The …

Occipital meningoencephalocele: report of two cases

F Kolsi, B Kammoun, ABEN SALAH, Y Gdoura… - CHIRURGIA …, 2018 - minervamedica.it
Meningoencephalocele is herniation of cerebrospinal fluid, brain tissue and meninges through
the skull defect. Occipital meningoencephalocele is a very rare type of neural tube defect. …

Naringenin protects cardiac hypercholesterolemia-induced oxidative stress and subsequent necroptosis in rats

Y Chtourou, AB Slima, M Makni, R Gdoura… - Pharmacological …, 2015 - Springer
Background In earlier studies, the supplementation of the natural compound Naringenin (NGEN),
improved the liver oxidative and inflammatory status, which indicates its direct effect via …

Protective effects of naringenin on iron-overload-induced cerebral cortex neurotoxicity correlated with oxidative stress

Y Chtourou, H Fetoui, R Gdoura - Biological trace element research, 2014 - Springer
Iron is a component of several metalloproteins involved in crucial metabolic processes such
as oxygen sensing and transport, energy metabolism, and DNA synthesis. This metal …

Naringenin reduces cholesterol-induced hepatic inflammation in rats by modulating matrix metalloproteinases-2, 9 via inhibition of nuclear factor κB pathway

…, R Jemai, AB Slima, M Makni, R Gdoura - European journal of …, 2015 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is a spectrum of hepatic abnormalities that extends
from isolated steatosis to non-alcoholic steatohepatitis (NASH) and steatofibrosis. NASH is …

Naringenin mitigates iron-induced anxiety-like behavioral impairment, mitochondrial dysfunctions, ectonucleotidases and acetylcholinesterase alteration activities in …

Y Chtourou, AB Slima, R Gdoura, H Fetoui - Neurochemical Research, 2015 - Springer
Studies demonstrated that the iron chelating antioxidant restores brain dysfunction induced
by iron toxicity in animals. Earlier, we found that iron overload-induced cerebral cortex …