To the editor—A critical feature of Alzheimer disease (AD) is the deposition of plaque, which
contains high levels of amyloid-β (Aβ) peptides1. A small subset of AD patients carry the …

Inflammation clearly occurs in pathologically vulnerable regions of the Alzheimer’s disease (AD)
brain, and it does so with the full complexity of local peripheral inflammatory responses. …

We have characterized amyloid β peptide (Aβ. concentration, Aβ deposition, paired helical
filament formation, cerebrovascular amyloid angiopathy, apolipoprotein E (ApoE) allotype, …

We have utilized the polymerase chain reaction technique to selectively amplify a G protein-coupled
receptor cDNA from rat kidney proximal convoluted tubule mRNA, which exhibits …

Much evidence indicates that women have a higher risk of developing Alzheimer's disease (AD)
than do men. The reason for this gender difference is unclear. We hypothesize that …

Neurodegenerative tauopathies characterized by hyperphosphorylated tau include
frontotemporal dementia and Parkinsonism linked to chromosome 17 (FTDP-17) and Alzheimer's …

Estrogens are the primary female sex hormones and play important roles in both reproductive
and non-reproductive systems. Estrogens can be synthesized in non-reproductive tissues …

We have used the polymerase chain reaction technique to selectively amplify a guanine
nucleotide-binding protein-coupled receptor cDNA sequence from rat striatal mRNA that …

Whether elevated β-secretase (BACE) activity is related to plaque formation or amyloid β
peptide (Aβ) production in Alzheimer's disease (AD) brains remains inconclusive. Here, we …

As the emerging variants of SARS-CoV-2 continue to drive the worldwide pandemic, there
is a constant demand for vaccines that offer more effective and broad-spectrum protection. …